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title: "Recent advancements in polyaniline-based biosensors for diagnosis of cancers: a comprehensive review" | ||
collection: publications | ||
permalink: /publication/18 | ||
excerpt: 'This review is about polyaniline-based nanobiosensors for setection of cancer biomarkers.' | ||
date: 2024-11-08 | ||
venue: 'Trends in Analytical Chemistry' | ||
paperurl: 'https://doi.org/10.1016/j.trac.2024.118040' | ||
--- | ||
<address class="author">Authors: Mojtaba Hosseine, <a rel="author" href="https://bakhshiali.github.io">Ali Bakhshi</a>, Seyed Morteza Naghib, Navid Rabiee | ||
</address><br> | ||
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<p align="justify" style="padding-left: 1em"> | ||
Recent advances in biosensor and bioelectronics technologies have revolutionized cancer diagnosis, providing more accessible, | ||
sensitive, and specific methods for early detection. This review focuses on polyaniline (PANI)-based biosensors, which demonstrate | ||
significant potential in detecting cancer biomarkers due to their tunable properties, cost-effectiveness, and ease of synthesis. | ||
Various PANI synthesis techniques, including chemical, electrochemical, enzyme-catalyzed, vapor-phase, and template-assisted | ||
polymerization, are examined, along with the development of multidimensional PANI nanostructures to enhance biosensor performance. | ||
Advanced 3D printing techniques have enabled the precise fabrication of PANI-based devices, such as flexible sensors, | ||
high-performance supercapacitors, and electroactive scaffolds, showcasing PANI's versatility and potential in biomedical | ||
and biosensor applications. The application of PANI-based biosensors in detecting lung, liver, breast, and prostate cancers | ||
is discussed, highlighting the detection principles, limits, and specificity for each cancer type. Furthermore, the role of | ||
PANI in signal amplification through nanocomposite (NC) integration, which improves diagnostic accuracy, is explored. | ||
This comprehensive review also addresses the current challenges and future opportunities for advancements in PANI-based | ||
biosensor technology, emphasizing its critical importance in the next generation of cancer diagnostics. By overcoming the | ||
limitations of conventional diagnostic methods, these biosensors are positioned to play a pivotal role in improving early | ||
cancer detection and patient outcomes. | ||
</p> | ||
<cite> Mojtaba Hosseine, Ali Bakhshi, Seyed Morteza Naghib, Navid Rabiee | ||
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: a comprehensive review, 118040 | ||
DOI: https://doi.org/10.1016/j.trac.2024.118040 | ||
</cite> | ||
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<b>Full-Texts</b> | ||
<details> | ||
<summary>Sciencedirect</summary> | ||
<a href="https://doi.org/10.1016/j.trac.2024.118040"> https://doi.org/10.1016/j.trac.2024.118040 </a> | ||
</details> | ||
<details> | ||
<summary>Researchgate</summary> | ||
<a href="https://www.researchgate.net/publication/385656766_Recent_advancements_in_polyaniline-based_biosensors_for_diagnosis_of_cancers_a_comprehensive_review"> https://www.researchgate.net/publication/385656766_Recent_advancements_in_polyaniline-based_biosensors_for_diagnosis_of_cancers_a_comprehensive_review </a> | ||
</details> |