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Create a folder that contains:
(1) your manifest.ini file (required, file 1) containing all necessary informations as explained here
(2) your data file (optional, file 2)
In your terminal, make sure that you are in the folder containing those files and enter the following command line:
tar –cvzf compressedfilename.tar.gz <file1> <file2>
You can now import the resulting tar.gz file in pyGeno as explained in the documentation.