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ADRD_Brain_Aging

ADRD Brain Aging projects

  • Phase 1: single-nuclei atlas between young and old subjects in four brain regions
    • Where 'young' subjects were between 20-30 years of age at time of death and 'old' were 60-80 years of age at time of death
    • brain regions included for each subject are: putamen, entorhinal cortex, middle temporal gyrus, and subventricular zone
  • Phase 2: future work
    • expansion in the number of subjects included and analyses using age as a continuous variable
    • focus on a single brain region for the expanded subject series

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