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@kcleal kcleal released this 26 Feb 11:17
· 4 commits to master since this release
79152b7

Improvements

  • SV phasing is now supported. Supply dysgu with a 'haplotagged' bam file (with HP and PS tags for reads) and dysgu will automatically phase output SVs. This results in a large increase in performance for long reads (see PacBio benchmark here: https://github.com/kcleal/SV_Benchmark_CMRG_GIAB)
  • Added AF allele frequency to FORMAT column #117
  • New progressive merge method when using dysgu merge that allows better scaling to large cohorts. This can be set using --merge-method [ auto | all-vs-all | progressive ], default is auto #82
  • Improvements to merging SVs during calling

Fixes

  • Fixed DUP sequences ending up in REF column #123