Update README.md

README.md

@@ -12,7 +12,7 @@ Genome-wide association studies (GWAS) have identified many common variants asso
 
 Epistasis has been proposed to underlie some of this "missing heritability" identified in the post-GWAS era, though this topic remains controversial ([Ritchie et al. 2015](https://pubmed.ncbi.nlm.nih.gov/25403525/); [Ritchie and Van Steen 2018](https://pubmed.ncbi.nlm.nih.gov/29862246/); [Bandres-Ciga et al. 2020](https://pubmed.ncbi.nlm.nih.gov/31991247/)). Epistasis occurs when there is an interaction between genetic variants. For example, an allele an locus 1 may prevent an alleles at locus 2 from manifesting ([Bateson 1909](https://scholar.google.com/scholar?q=Bateson,+W.+(1909)+Mendel%27s+Principles+of+Heredity.+Cambridge+University+Press,+Cambridge.)), a phenomenon known as masking.
 
-The concept of epistasis has been extensively studied in model systems, but its importance in humans continues to be a matter of debate ([Carlborg and Haley 2004](https://pubmed.ncbi.nlm.nih.gov/15266344/);[Ritchie and Van Steen 2018](https://pubmed.ncbi.nlm.nih.gov/29862246/)). One of the reasons for this discussion is that there is a no of consensus on the methods used to perform epistasis analyses and replication studies are required. 
+The concept of epistasis has been extensively studied in model systems, but its importance in humans continues to be a matter of debate ([Carlborg and Haley 2004](https://pubmed.ncbi.nlm.nih.gov/15266344/); [Ritchie and Van Steen 2018](https://pubmed.ncbi.nlm.nih.gov/29862246/)). One of the reasons for this discussion is that there is a no of consensus on the methods used to perform epistasis analyses and replication studies are required. 
 
 The current project is a variant interaction pipeline built as part of the IPDGC x GP2 Hackathon 2021 Project to start a collaborative environment to generate a user friendly tool to investigate epistasis between pairs of variants provided by the user.