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title: "Chapter 18 - Multifunctional theranostic nanomedicine for infectious diseases" | ||
collection: publications | ||
permalink: /publication/19 | ||
excerpt: 'This chapter is about multifunctional theranostic nanomedicine for infectious diseases.' | ||
date: 2024-10-31 | ||
venue: 'Elsevier' | ||
paperurl: 'https://doi.org/10.1016/B978-0-443-22044-9.00021-8' | ||
--- | ||
<address class="author">Authors: <a rel="author" href="https://bakhshiali.github.io">Ali Bakhshi</a>, Mahya Bakhshi, Bahar Ahmadi, Abbas Rahdar | ||
</address><br> | ||
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<p align="justify" style="padding-left: 1em"> | ||
Infectious diseases remain a significant global burden, with the rise of multidrug resistant pathogens and the limitations of conventional | ||
antibiotics posing a critical challenge. Multifunctional theranostic nanomedicine is an innovative approach to treat infectious diseases. | ||
It combines diagnosis and treatment into a single platform, offering targeted delivery, enhanced efficacy, real-time monitoring, and even | ||
personalized medicine. Nanocarriers can overcome the defenses of various pathogens, like bacteria with their walls and fungi with their | ||
biofilms, delivering drugs precisely to the target. For instance, in bacteria, nanocarriers can overcome formidable cell walls and efflux | ||
pumps. They can also be equipped with imaging agents like quantum dots to track their progress, enabling real-time monitoring of drug delivery, | ||
treatment response, and even pathogen localization. Importantly, their surface can be modified to evade immune clearance and equipped with | ||
targeting ligands for specific pathogens. Stimuli-responsive nanomedicine can control the spread and growth of pathogens by applying external | ||
or internal signals. Innovative synthesis and production methods can facilitate the development of various drug administration and delivery | ||
strategies on the molecular scale. Such developments lead to innovations in microfluidics, microneedle patches, bioimplants, multifunctional | ||
biopolymers, encapsulations, and stimuli-responsive multitargeting formulations. While challenges remain, like safety testing and overcoming | ||
biological barriers, the future of this technology is bright with advancements in materials, printing, and machine learning algorithms. | ||
This revolutionary approach has the potential to control and even eradicate infectious diseases, offering a beacon of hope for global health. | ||
</p> | ||
<cite> Ali Bakhshi, Mahya Bakhshi, Bahar Ahmadi, Abbas Rahdar | ||
Chapter 18 - Multifunctional theranostic nanomedicine for infectious diseases, 339-362 | ||
DOI: https://doi.org/10.1016/B978-0-443-22044-9.00021-8 | ||
</cite> | ||
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<b>Full-Texts</b> | ||
<details> | ||
<summary>Elsevier</summary> | ||
<a href="https://www.sciencedirect.com/science/article/abs/pii/B9780443220449000218"> https://www.sciencedirect.com/science/article/abs/pii/B9780443220449000218 </a> | ||
</details> | ||
<details> | ||
<summary>Researchgate</summary> | ||
<a href="https://www.sciencedirect.com/science/article/abs/pii/B9780443220449000218"> https://www.sciencedirect.com/science/article/abs/pii/B9780443220449000218 </a> | ||
</details> |