Data Analysis of Onchocerciasis Disease in Sierra Leone, Africa

Data

• Data used : Secondary data on Onchocerciasis (River-blindness) from Sierra Leone, Africa

• Dataset Variables:

  • id - Unique number
  • mf - Microfilaria Infection: 1 = yes, 0 = no
  • area - Area of residdence: 1 = Rainforest, 0 = Savannah
  • agegrp - Age Group(years): 0 = 5-9, 1 = 10-19, 2 = 20-39, 3 = 40+
  • sex - 0 = male, 1 = female
  • lesions - Eye Lesions: 0 = yes, 0 = no

• Null hypothesis: Living in the Rainforest or Savannah area does not affect the risk of having Microfilarial Infection.

Methods

• Exploratory Analysis
• Linear Regression

Software and Packages used

• R, RStudio
• gtsummary, readxl, tibble, Hmisc, purrr

Exploratory Analysis Results

• Population: 1302
• Comparison: rainforest, savnnah
• Confounding: Sex, Age
• Primary Outcome: Microfilaria Infection
• Secondary Outcome: Eye Lesions

Conclusions

• The risk of Microfilarial Infection at baseline is 0.689 .
• In Rainforest area, the risk is 0.789, while in Savannah area it is 0.515.
• The area that people are living in has biggest influence on the risk of Microfilarial Infection.
• Age group and sex affect the risk of infection.
• Elder people are more likely to get infected.
• Male have higher risk of infection.