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Minimal model of interictal and ictal discharges “Epileptor-2” (Chizhov et al 2018)
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<html> <p> This is the readme for the models associated with the paper</p> <p>Chizhov AV, Zefirov AV, Amakhin DV, Smirnova EY, Zaitsev AV (2018) Minimal model of interictal and ictal discharges "Epileptor-2". PLoS Comput Biol 14:e1006186<br/> doi: <a href="http://dx.doi.org/10.1371/journal.pcbi.1006186">10.1371/journal.pcbi.1006186</a> </p> <p>This model entry was contributed by AV Chizhov. </p> <p>This excerpt from the paper provides some specifics. Although the drive.google.com links are broken the model code is available in this modeldb entry: </p> <p>"The simulations were performed in the Delphi-7 environment. The mathematical analysis of the stochastic oscillations was performed using Wolfram Mathematica 10 (Champaign, IL, USA). The Euler-Maruyama explicit numerical scheme was applied for the integration of the stochastic ordinary differential equations. The typical value of a time step was 0.5 ms. The results were dependent on the numerical parameter in a similar extent as for different realizations of noise. The numerical realizations of the model are available from the websites: the code in Wolfram Mathematica is at <a href="https://yadi.sk/d/927UjbS-3QQhMW;">https://yadi.sk/d/927UjbS-3QQhMW;</a> the code and executive file in Delphi-Pascal are at <a href="https://drive.google.com/file/d/1AJhAFKLOjvgauBF_6SQzvol8zzmfMaDV/view?usp=sharing">https://drive.google.com/file/d/1AJhAFKLOjvgauBF_6SQzvol8zzmfMaDV/view?usp=sharing</a> and<br/> <a href="https://drive.google.com/open?id=10ij-Nt780jROcMv9qniUm4rAJNr8WD2j">https://drive.google.com/open?id=10ij-Nt780jROcMv9qniUm4rAJNr8WD2j"</a> , correspondingly." </p> <p> Python and JavaScript versions of Epileptor-2 are also available under the subfolders of the same name. </p> <p>The JavaScript version (available in the html file) produces the following after this archive is downloaded, extracted, and the html file is loaded into a browser (will not run from ModelDB): </p> <p><img src="./screenshot.png" alt="screenshot" width="650"></p> <p>The python (verified in Python 3.6.9) version produces the following graphs</p> <img src="./screenshot2.png" alt="screenshot 2"> <p>The code has been originally written by me (AV Chizhov) in Delphi. It was later re-implemented in Python by Artyom Zefirov, in Wolfram Mathematica by Dmitry Amakhin, and in Javascript by me.</p> <p>20200514 update from AV Chizhov to provide corrected Python file.</p> </html>
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