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## 2024 Releases

### [v2024-11-01](https://github.com/DiseaseOntology/HumanDiseaseOntology/tree/v2024-11-01)
### [v2024-11-27](https://github.com/DiseaseOntology/HumanDiseaseOntology/tree/v2024-11-27)

This release of the Human Disease Ontology includes 11,684 disease classes, 9,358 with textual definitions (80.0%).
This release of the Human Disease Ontology includes 11,708 disease classes, 9,383 with textual definitions (80.1%).

New diseases include autoinflammatory syndrome, ring chromosome syndromes, and new subtypes for AML, B-ALL, congenital amegakaryocytic thrombocytopenia, advanced sleep phase syndrome, sideroblastic anemia, craniosynostosis, and ovarian dysgenesis.

Diseases that have been revised and/or updated with additional subtypes include glycine encephalopathies, FACS, mitochondrial trifunctional protein deficiencies, autosomal dominant isolated macrothrombocytopenias, poor metabolism of thiopurines, retinitis pigmentosa 17, and Axenfeld-Rieger syndrome.
Disease classifications have been revised to fix malignant mesotheliomas and to reclassify autoinflammatory syndromes under this new term including: proteosome-associated autoinflammatory syndrome, congenital amegakaryocytic thrombocytopenia, familial Behcet-like autoinflammatory syndrome, familial cold autoinflammatory syndrome, familial Mediterranean fever, and TNF receptor-associated periodic syndrome.

New diseases include APLAID, striatal degeneration 2, congenital amegakaryocytic thrombocytopenia 2, and rhabdoid tumor predisposition syndrome with subtypes.
Additional revisions include the definitions of MASLD, MetALD, and congenital disorder of deglycosylation; added cross-references for B-ALL subtypes; and updated definition sources to replace inaccessible sources.

This release also includes a new subset focused on childhood cancers `DO_childhood_cancer_slim` and a minor change to the DO_MGI_slim, as well as, expanded chest-related anatomical and onset logical axioms.
### Obsoleted disease(s)
ID | label | term replaced by
--- | --- | ---
DOID:0080546 | non-alcoholic fatty liver | metabolic dysfunction-associated steatotic liver disease (DOID:0080208)

</br>

**Full Changelog**: https://github.com/DiseaseOntology/HumanDiseaseOntology/compare/v2024-11-01...v2024-11-27

| | OWL | OBO | JSON |
| --- | --- | --- | --- |
| Disease Ontology | [doid.owl](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid.owl) | [doid.obo](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid.obo) | [doid.json](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid.json) |
| Human DO | [HumanDO.owl](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/HumanDO.owl) | [HumanDO.obo](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/HumanDO.obo) | |
| DO Non-Classified | [doid-non-classified.owl](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid-non-classified.owl) | [doid-non-classified.obo](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid-non-classified.obo) | [doid-non-classified.json](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid-non-classified.json) |
| DO Merged | [doid-merged.owl](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid-merged.owl) | [doid-merged.obo](https://raw.githubusercontent.com/DiseaseOntology/HumanDiseaseOntology/v2024-11-27/src/ontology/doid-merged.obo) | |

### [v2024-11-01](https://github.com/DiseaseOntology/HumanDiseaseOntology/tree/v2024-11-01)

This release of the Human Disease Ontology includes 11,684 disease classes, 9,358 with textual definitions (80.0%).

Diseases that have been revised and/or updated with additional subtypes include glycine encephalopathies, FACS, mitochondrial trifunctional protein deficiencies, autosomal dominant isolated macrothrombocytopenias, poor metabolism of thiopurines, retinitis pigmentosa 17, and Axenfeld-Rieger syndrome.

New diseases include APLAID, striatal degeneration 2, congenital amegakaryocytic thrombocytopenia 2, and rhabdoid tumor predisposition syndrome with subtypes.

This release also includes a new subset focused on childhood cancers `DO_childhood_cancer_slim` and a minor change to the DO_MGI_slim, as well as, expanded chest-related anatomical and onset logical axioms.

**Full Changelog**: https://github.com/DiseaseOntology/HumanDiseaseOntology/compare/v2024-09-27...v2024-11-01

| | OWL | OBO | JSON |
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