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External resources #8

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Expand Up @@ -182,6 +182,39 @@ Cross references to the [Experimental Factor Ontology (EFO)](https://www.ebi.ac.

Cross-links to [ChEMBL](https://www.ebi.ac.uk/chembl/) are used to indicate complexes which have been used as drug targets.

### External resources

<table>
<thead>
<tr>
<th>Identifier</th>
<th>Qualifier</th>
<th>Description</th>
</tr>
</thead>
<tbody>
<tr>
<td rowspan=5>
<a href="https://www.ebi.ac.uk/emdb">EMDB</a><br>
<a href="https://humap3.proteincomplexes.org">Hu.MAP3.0</a><br>
<a href="http://www.ebi.ac.uk/pdbe">PDB</a><br>
</td>
<td><a href="https://www.ebi.ac.uk/ols4/ontologies/mi/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FMI_0356" target="_blank">Identical object in an external resource</a></td>
<td>Components in the Complex Portal complex and hu.MAP3.0 cluster or PDB/EMDB structure are identical. </td>
</tr>
<tr></tr>
<tr>
<td><a href="https://www.ebi.ac.uk/ols4/ontologies/mi/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FMI_2179" target="_blank">Subset</a></td>
<td>A partial match with additional complex components in the Complex Portal complex. </td>
</tr>
<tr></tr>
<tr>
<td><a href="https://www.ebi.ac.uk/ols4/ontologies/mi/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FMI_2427" target="_blank">Complex-cluster</a></td>
<td>Two or more complexes in the Complex Portal are a subset of a single hu.MAP3.0 entry with the difference being due to the clustering of paralogs in the hu.MAP3.0 complex.</td>
</tr>
</tbody>
</table>

## Complex Variants

If variant forms of a complex exist i.e. the same functional unit can exist in alternate forms with differing macromolecular composition, these are curated as separate objects. For example, PDGF can exist as a PDGF-A homodimer, PDGF-B homodimer, PDGF-AB heterodimer, PDGF-C homodimer and a PDGF-D homodimer. If the variants have well-accepted names, e.g. PDGF-AB, these may be used as the primary name. If not, then the recommended name is qualified by variant 1, variant 2 e.g. [TRAMP complex variant 1](https://www.ebi.ac.uk/complexportal/complex/CPX-1678).
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