Merge pull request #7 from Complex-Portal/update-complex-definition-2

Update complex definition 2

about/overview.md

@@ -1,10 +1,12 @@
 ## Overview of Complex Portal
 
-The Complex Portal is a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms. 
+The Complex Portal is primarily a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms.
 
 Complexes are defined as an assembly of any two or more proteins and/or nucleic acids that are stable enough in vitro to be reconstituted and have been demonstrated to have a specific molecular function. They may also contain small molecules if they are essential, functional components.
 
-All complexes are derived from physical molecular interaction evidences extracted and cross-referenced from the literature and cross-referenced to the Molecular Interaction Database [IntAct](https://www.ebi.ac.uk/intact/) where available, or by curator inference from information on homologs in closely related species or by inference from scientific background. All complexes are tagged with [Evidence and Conclusion Ontology](https://www.ebi.ac.uk/ols/ontologies/eco) codes to indicate the type of evidence available for each entry.
+In addition to the manually curated complexes, which adhere to this definition, the database provides extended coverage of the human complexome with high confidence assemblies of machine-learning predicted complexes.
+
+All manually curated complexes are derived from physical molecular interaction evidences extracted and cross-referenced from the literature and cross-referenced to the Molecular Interaction Database [IntAct](https://www.ebi.ac.uk/intact/) where available, or by curator inference from information on homologs in closely related species or by inference from scientific background. All manually curated complexes are tagged with [Evidence and Conclusion Ontology](https://www.ebi.ac.uk/ols/ontologies/eco) codes to indicate the type of evidence available for each entry.
 
 **Special considerations:**
 

documentation/cp_content.md

@@ -4,9 +4,11 @@
 
 The Complex Portal is a manually curated, encyclopedic resource of biologically functional and stable macromolecular complexes from a number of key model organisms. Complexes may contain proteins as well as small molecules and nucleic acids, providing they are an integral part of the complex.
 
+In addition to the manually curated complexes, which adhere to this definition, the database provides extended coverage of the human complexome with high confidence assemblies of machine-learning predicted complexes.
+
 ### What can be described as a complex?
 
-A stable set of (two or more) interacting macromolecules such as proteins which can be co-purified by an acceptable method and have been shown to exist as an isolated, functional unit in vivo. This definition has been extended to encompass molecules which associate to form scaffolding structures that are ready to recruit context-specific effector proteins to initiate activation of functionally distinct signalling pathways within the same physical multiprotein complexes. Any interacting, integral non-protein molecules (e.g. small molecules, nucleic acids) may also be included. In addition to the manually curated complexes, which adhere to this definition, the database provides extended coverage of the human complexome with high confidence assemblies of machine-learning predicted complexes.
+A stable set of (two or more) interacting macromolecules such as proteins which can be co-purified by an acceptable method and have been shown to exist as an isolated, functional unit in vivo. This definition has been extended to encompass molecules which associate to form scaffolding structures that are ready to recruit context-specific effector proteins to initiate activation of functionally distinct signalling pathways within the same physical multiprotein complexes. Any interacting, integral non-protein molecules (e.g. small molecules, nucleic acids) may also be included.
 
 ### What should **NOT** be captured: