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typo fix
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ilkilic committed Nov 1, 2024
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"source": [
"# Building an E-Model for a single-compartment cell\n",
"\n",
"This notebook provides a simple example on how to run the pipeline to create an e-model of a single-compartment cell with two free parameters. In this instance, we will use \"rheobase independent\" optimisation. \n",
"This notebook provides a simple example on how to run the pipeline to create an e-model of a single-compartment cell with two free parameters. In this instance, we will use rheobase independent optimisation. \n",
"\n",
"When the optimisation is \"rheobase dependent,\" it means that we need to calculate the rheobase value (the minimum current required to trigger a neuron) to normalise the trace values. In this case, the normalisation is done by expressing the trace values as a percentage of the rheobase. This approach ensures that the traces are scaled relative to the neuron’s threshold current, providing a consistent basis for comparison. \n",
"When the optimisation is rheobase dependent, it means that we need to calculate the rheobase value (the minimum current required to trigger a neuron) to normalise the trace values. In this case, the normalisation is done by expressing the trace values as a percentage of the rheobase. This approach ensures that the traces are scaled relative to the neuron’s threshold current, providing a consistent basis for comparison. \n",
"\n",
"However, here we will present the rheobase independent approach which means that we use specific amplitude values like `IDRest_1.0` (indicating a fixed current of 1.0 nA) instead of `IDRest_100` (which represents 100% of the rheobase).\n",
"\n",
"For \"rheobase dependent\" optimisation or additional details, please refer to the [L5PC](./../L5PC/) example."
"For rheobase dependent optimisation or additional details, please refer to the [L5PC](./../L5PC/) example."
]
},
{
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