diff --git a/Cargo.toml b/Cargo.toml
index c6db2ed..8e35886 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -12,7 +12,6 @@ readme = "README.md"
 edition = "2018"
 
 [dependencies]
-libc = "0.2.58"
 cfg-if = "1.0.0"
 
 [target.'cfg(windows)'.dependencies.windows-sys]
@@ -23,5 +22,11 @@ features = [
     "Win32_System_IO",
 ]
 
+[target.'cfg(unix)'.dependencies]
+rustix = "0.31.0"
+
+[target.'cfg(windows)'.dependencies]
+io-lifetimes = { version = "0.4.0", default-features = false }
+
 [dev-dependencies]
 tempfile = "3.0.8"
diff --git a/README.md b/README.md
index db00f1d..3a9b856 100644
--- a/README.md
+++ b/README.md
@@ -38,7 +38,7 @@ $ cargo add fd-lock
 ```
 
 ## Safety
-This crate uses `unsafe` to interface with `libc` and `winapi`. All invariants
+This crate uses `unsafe` on Windows to interface with `winapi`. All invariants
 have been carefully checked, and are manually enforced.
 
 ## Contributing
@@ -51,7 +51,7 @@ look at some of these issues:
 ## References
 - [LockFile function - WDC](https://docs.microsoft.com/en-us/windows/desktop/api/fileapi/nf-fileapi-lockfile)
 - [flock(2) - Linux Man Page](https://linux.die.net/man/2/flock)
-- [`libc::flock`](https://docs.rs/libc/0.2.58/libc/fn.flock.html)
+- [`rustix::fs::flock`](https://docs.rs/rustix/*/rustix/fs/fn.flock.html)
 - [`winapi::um::fileapi::LockFile`](https://docs.rs/winapi/0.3.7/x86_64-pc-windows-msvc/winapi/um/fileapi/fn.LockFile.html)
 
 ## License
diff --git a/src/lib.rs b/src/lib.rs
index 9d3d619..6547cb0 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -31,6 +31,7 @@
 #![forbid(future_incompatible)]
 #![deny(missing_debug_implementations, nonstandard_style)]
 #![cfg_attr(doc, warn(missing_docs, rustdoc::missing_doc_code_examples))]
+#![cfg_attr(io_lifetimes_use_std, feature(io_safety))]
 
 mod read_guard;
 mod rw_lock;
diff --git a/src/sys/mod.rs b/src/sys/mod.rs
index 3c6391e..6e7af2a 100644
--- a/src/sys/mod.rs
+++ b/src/sys/mod.rs
@@ -4,12 +4,12 @@ cfg_if! {
     if #[cfg(unix)] {
         mod unix;
         pub use unix::*;
-        pub(crate) use std::os::unix::prelude::AsRawFd as AsRaw;
+        pub(crate) use rustix::fd::AsFd as AsRaw;
     } else if #[cfg(windows)] {
         mod windows;
         pub use windows::*;
         #[doc(no_inline)]
-        pub(crate) use std::os::windows::prelude::AsRawHandle as AsRaw;
+        pub(crate) use io_lifetimes::AsHandle as AsRaw;
     } else {
         mod unsupported;
         pub use unsupported;
diff --git a/src/sys/unix/mod.rs b/src/sys/unix/mod.rs
index 9d7bd2c..023e691 100644
--- a/src/sys/unix/mod.rs
+++ b/src/sys/unix/mod.rs
@@ -2,8 +2,6 @@ mod read_guard;
 mod rw_lock;
 mod write_guard;
 
-pub(crate) mod utils;
-
 pub use read_guard::RwLockReadGuard;
 pub use rw_lock::RwLock;
 pub use write_guard::RwLockWriteGuard;
diff --git a/src/sys/unix/read_guard.rs b/src/sys/unix/read_guard.rs
index bf7490b..c26203b 100644
--- a/src/sys/unix/read_guard.rs
+++ b/src/sys/unix/read_guard.rs
@@ -1,22 +1,21 @@
-use libc::{flock, LOCK_UN};
+use rustix::fs::{flock, FlockOperation};
+use rustix::fd::AsFd;
 use std::ops;
-use std::os::unix::io::AsRawFd;
 
-use super::utils::syscall;
 use super::RwLock;
 
 #[derive(Debug)]
-pub struct RwLockReadGuard<'lock, T: AsRawFd> {
+pub struct RwLockReadGuard<'lock, T: AsFd> {
     lock: &'lock RwLock<T>,
 }
 
-impl<'lock, T: AsRawFd> RwLockReadGuard<'lock, T> {
+impl<'lock, T: AsFd> RwLockReadGuard<'lock, T> {
     pub(crate) fn new(lock: &'lock RwLock<T>) -> Self {
         Self { lock }
     }
 }
 
-impl<T: AsRawFd> ops::Deref for RwLockReadGuard<'_, T> {
+impl<T: AsFd> ops::Deref for RwLockReadGuard<'_, T> {
     type Target = T;
 
     #[inline]
@@ -25,10 +24,10 @@ impl<T: AsRawFd> ops::Deref for RwLockReadGuard<'_, T> {
     }
 }
 
-impl<T: AsRawFd> Drop for RwLockReadGuard<'_, T> {
+impl<T: AsFd> Drop for RwLockReadGuard<'_, T> {
     #[inline]
     fn drop(&mut self) {
-        let fd = self.lock.inner.as_raw_fd();
-        let _ = syscall(unsafe { flock(fd, LOCK_UN) });
+        let fd = self.lock.inner.as_fd();
+        let _ = flock(&fd, FlockOperation::Unlock).ok();
     }
 }
diff --git a/src/sys/unix/rw_lock.rs b/src/sys/unix/rw_lock.rs
index 70c9860..6c7d25f 100644
--- a/src/sys/unix/rw_lock.rs
+++ b/src/sys/unix/rw_lock.rs
@@ -1,16 +1,15 @@
-use libc::{flock, LOCK_EX, LOCK_NB, LOCK_SH};
+use rustix::fs::{flock, FlockOperation};
+use rustix::fd::AsFd;
 use std::io::{self, Error, ErrorKind};
-use std::os::unix::io::AsRawFd;
 
-use super::utils::syscall;
 use super::{RwLockReadGuard, RwLockWriteGuard};
 
 #[derive(Debug)]
-pub struct RwLock<T: AsRawFd> {
+pub struct RwLock<T: AsFd> {
     pub(crate) inner: T,
 }
 
-impl<T: AsRawFd> RwLock<T> {
+impl<T: AsFd> RwLock<T> {
     #[inline]
     pub fn new(inner: T) -> Self {
         RwLock { inner }
@@ -18,34 +17,34 @@ impl<T: AsRawFd> RwLock<T> {
 
     #[inline]
     pub fn write(&mut self) -> io::Result<RwLockWriteGuard<'_, T>> {
-        let fd = self.inner.as_raw_fd();
-        syscall(unsafe { flock(fd, LOCK_EX) })?;
+        let fd = self.inner.as_fd();
+        flock(&fd, FlockOperation::LockExclusive)?;
         Ok(RwLockWriteGuard::new(self))
     }
 
     #[inline]
     pub fn try_write(&mut self) -> Result<RwLockWriteGuard<'_, T>, Error> {
-        let fd = self.inner.as_raw_fd();
-        syscall(unsafe { flock(fd, LOCK_EX | LOCK_NB) }).map_err(|err| match err.kind() {
+        let fd = self.inner.as_fd();
+        flock(&fd, FlockOperation::NonBlockingLockExclusive).map_err(|err| match err.kind() {
             ErrorKind::AlreadyExists => ErrorKind::WouldBlock.into(),
-            _ => err,
+            _ => Error::from(err),
         })?;
         Ok(RwLockWriteGuard::new(self))
     }
 
     #[inline]
     pub fn read(&self) -> io::Result<RwLockReadGuard<'_, T>> {
-        let fd = self.inner.as_raw_fd();
-        syscall(unsafe { flock(fd, LOCK_SH) })?;
+        let fd = self.inner.as_fd();
+        flock(&fd, FlockOperation::LockShared)?;
         Ok(RwLockReadGuard::new(self))
     }
 
     #[inline]
     pub fn try_read(&self) -> Result<RwLockReadGuard<'_, T>, Error> {
-        let fd = self.inner.as_raw_fd();
-        syscall(unsafe { flock(fd, LOCK_SH | LOCK_NB) }).map_err(|err| match err.kind() {
+        let fd = self.inner.as_fd();
+        flock(&fd, FlockOperation::NonBlockingLockShared).map_err(|err| match err.kind() {
             ErrorKind::AlreadyExists => ErrorKind::WouldBlock.into(),
-            _ => err,
+            _ => Error::from(err),
         })?;
         Ok(RwLockReadGuard::new(self))
     }
diff --git a/src/sys/unix/utils.rs b/src/sys/unix/utils.rs
deleted file mode 100644
index 191dd0c..0000000
--- a/src/sys/unix/utils.rs
+++ /dev/null
@@ -1,9 +0,0 @@
-use std::io;
-use std::os::raw::c_int;
-
-pub(crate) fn syscall(int: c_int) -> io::Result<()> {
-    match int {
-        0 => Ok(()),
-        _ => Err(io::Error::last_os_error()),
-    }
-}
diff --git a/src/sys/unix/write_guard.rs b/src/sys/unix/write_guard.rs
index 6060d60..29beccd 100644
--- a/src/sys/unix/write_guard.rs
+++ b/src/sys/unix/write_guard.rs
@@ -1,22 +1,21 @@
-use libc::{flock, LOCK_UN};
+use rustix::fs::{flock, FlockOperation};
+use rustix::fd::AsFd;
 use std::ops;
-use std::os::unix::io::AsRawFd;
 
-use super::utils::syscall;
 use super::RwLock;
 
 #[derive(Debug)]
-pub struct RwLockWriteGuard<'lock, T: AsRawFd> {
+pub struct RwLockWriteGuard<'lock, T: AsFd> {
     lock: &'lock mut RwLock<T>,
 }
 
-impl<'lock, T: AsRawFd> RwLockWriteGuard<'lock, T> {
+impl<'lock, T: AsFd> RwLockWriteGuard<'lock, T> {
     pub(crate) fn new(lock: &'lock mut RwLock<T>) -> Self {
         Self { lock }
     }
 }
 
-impl<T: AsRawFd> ops::Deref for RwLockWriteGuard<'_, T> {
+impl<T: AsFd> ops::Deref for RwLockWriteGuard<'_, T> {
     type Target = T;
 
     #[inline]
@@ -25,17 +24,17 @@ impl<T: AsRawFd> ops::Deref for RwLockWriteGuard<'_, T> {
     }
 }
 
-impl<T: AsRawFd> ops::DerefMut for RwLockWriteGuard<'_, T> {
+impl<T: AsFd> ops::DerefMut for RwLockWriteGuard<'_, T> {
     #[inline]
     fn deref_mut(&mut self) -> &mut Self::Target {
         &mut self.lock.inner
     }
 }
 
-impl<T: AsRawFd> Drop for RwLockWriteGuard<'_, T> {
+impl<T: AsFd> Drop for RwLockWriteGuard<'_, T> {
     #[inline]
     fn drop(&mut self) {
-        let fd = self.lock.inner.as_raw_fd();
-        let _ = syscall(unsafe { flock(fd, LOCK_UN) });
+        let fd = self.lock.inner.as_fd();
+        let _ = flock(&fd, FlockOperation::Unlock).ok();
     }
 }
diff --git a/src/sys/unsupported/read_guard.rs b/src/sys/unsupported/read_guard.rs
index c0ea175..7d6b4c7 100644
--- a/src/sys/unsupported/read_guard.rs
+++ b/src/sys/unsupported/read_guard.rs
@@ -1,8 +1,6 @@
-use libc::{flock, LOCK_UN};
 use std::ops;
 use std::os::unix::io::AsRawFd;
 
-use super::utils::syscall;
 use super::RwLock;
 
 #[derive(Debug)]
diff --git a/src/sys/unsupported/rw_lock.rs b/src/sys/unsupported/rw_lock.rs
index 856e5d7..fb11da8 100644
--- a/src/sys/unsupported/rw_lock.rs
+++ b/src/sys/unsupported/rw_lock.rs
@@ -1,8 +1,6 @@
-use libc::{flock, LOCK_EX, LOCK_NB, LOCK_SH};
 use std::io::{self, Error, ErrorKind};
 use std::os::unix::io::AsRawFd;
 
-use super::utils::syscall;
 use super::{RwLockReadGuard, RwLockWriteGuard};
 
 #[derive(Debug)]
diff --git a/src/sys/unsupported/write_guard.rs b/src/sys/unsupported/write_guard.rs
index 28a6a64..19727c3 100644
--- a/src/sys/unsupported/write_guard.rs
+++ b/src/sys/unsupported/write_guard.rs
@@ -1,8 +1,6 @@
-use libc::{flock, LOCK_UN};
 use std::ops;
 use std::os::unix::io::AsRawFd;
 
-use super::utils::syscall;
 use super::RwLock;
 
 #[derive(Debug)]
diff --git a/src/sys/windows/read_guard.rs b/src/sys/windows/read_guard.rs
index 88258eb..af902d8 100644
--- a/src/sys/windows/read_guard.rs
+++ b/src/sys/windows/read_guard.rs
@@ -1,3 +1,4 @@
+use io_lifetimes::AsHandle;
 use windows_sys::Win32::Storage::FileSystem::UnlockFile;
 
 use std::ops;
@@ -7,11 +8,11 @@ use super::utils::syscall;
 use super::RwLock;
 
 #[derive(Debug)]
-pub struct RwLockReadGuard<'lock, T: AsRawHandle> {
+pub struct RwLockReadGuard<'lock, T: AsHandle> {
     pub(crate) lock: &'lock RwLock<T>,
 }
 
-impl<T: AsRawHandle> ops::Deref for RwLockReadGuard<'_, T> {
+impl<T: AsHandle> ops::Deref for RwLockReadGuard<'_, T> {
     type Target = T;
 
     #[inline]
@@ -20,10 +21,10 @@ impl<T: AsRawHandle> ops::Deref for RwLockReadGuard<'_, T> {
     }
 }
 
-impl<T: AsRawHandle> Drop for RwLockReadGuard<'_, T> {
+impl<T: AsHandle> Drop for RwLockReadGuard<'_, T> {
     #[inline]
     fn drop(&mut self) {
-        let handle = self.lock.inner.as_raw_handle();
+        let handle = self.lock.inner.as_handle().as_raw_handle();
         syscall(unsafe { UnlockFile(handle, 0, 0, 1, 0) })
             .expect("Could not unlock the file descriptor");
     }
diff --git a/src/sys/windows/rw_lock.rs b/src/sys/windows/rw_lock.rs
index 15ded19..8f01741 100644
--- a/src/sys/windows/rw_lock.rs
+++ b/src/sys/windows/rw_lock.rs
@@ -1,3 +1,4 @@
+use io_lifetimes::AsHandle;
 use std::io::{self, Error, ErrorKind};
 use std::os::windows::io::AsRawHandle;
 
@@ -9,11 +10,11 @@ use super::utils::{syscall, Overlapped};
 use super::{RwLockReadGuard, RwLockWriteGuard};
 
 #[derive(Debug)]
-pub struct RwLock<T: AsRawHandle> {
+pub struct RwLock<T: AsHandle> {
     pub(crate) inner: T,
 }
 
-impl<T: AsRawHandle> RwLock<T> {
+impl<T: AsHandle> RwLock<T> {
     #[inline]
     pub fn new(inner: T) -> Self {
         RwLock { inner }
@@ -22,7 +23,7 @@ impl<T: AsRawHandle> RwLock<T> {
     #[inline]
     pub fn read(&self) -> io::Result<RwLockReadGuard<'_, T>> {
         // See: https://stackoverflow.com/a/9186532, https://docs.microsoft.com/en-us/windows/win32/api/fileapi/nf-fileapi-lockfileex
-        let handle = self.inner.as_raw_handle();
+        let handle = self.inner.as_handle().as_raw_handle();
         let overlapped = Overlapped::zero();
         let flags = 0;
         syscall(unsafe { LockFileEx(handle, flags, 0, 1, 0, overlapped.raw()) })?;
@@ -31,7 +32,7 @@ impl<T: AsRawHandle> RwLock<T> {
 
     #[inline]
     pub fn try_read(&self) -> io::Result<RwLockReadGuard<'_, T>> {
-        let handle = self.inner.as_raw_handle();
+        let handle = self.inner.as_handle().as_raw_handle();
         let overlapped = Overlapped::zero();
         let flags = LOCKFILE_FAIL_IMMEDIATELY;
 
@@ -43,7 +44,7 @@ impl<T: AsRawHandle> RwLock<T> {
     #[inline]
     pub fn write(&mut self) -> io::Result<RwLockWriteGuard<'_, T>> {
         // See: https://stackoverflow.com/a/9186532, https://docs.microsoft.com/en-us/windows/win32/api/fileapi/nf-fileapi-lockfileex
-        let handle = self.inner.as_raw_handle();
+        let handle = self.inner.as_handle().as_raw_handle();
         let overlapped = Overlapped::zero();
         let flags = LOCKFILE_EXCLUSIVE_LOCK;
         syscall(unsafe { LockFileEx(handle, flags, 0, 1, 0, overlapped.raw()) })?;
@@ -52,7 +53,7 @@ impl<T: AsRawHandle> RwLock<T> {
 
     #[inline]
     pub fn try_write(&mut self) -> io::Result<RwLockWriteGuard<'_, T>> {
-        let handle = self.inner.as_raw_handle();
+        let handle = self.inner.as_handle().as_raw_handle();
         let overlapped = Overlapped::zero();
         let flags = LOCKFILE_FAIL_IMMEDIATELY | LOCKFILE_EXCLUSIVE_LOCK;
 
diff --git a/src/sys/windows/write_guard.rs b/src/sys/windows/write_guard.rs
index cb1d9b3..6e22e34 100644
--- a/src/sys/windows/write_guard.rs
+++ b/src/sys/windows/write_guard.rs
@@ -1,3 +1,4 @@
+use io_lifetimes::AsHandle;
 use windows_sys::Win32::Storage::FileSystem::UnlockFile;
 
 use std::ops;
@@ -7,11 +8,11 @@ use super::utils::syscall;
 use super::RwLock;
 
 #[derive(Debug)]
-pub struct RwLockWriteGuard<'lock, T: AsRawHandle> {
+pub struct RwLockWriteGuard<'lock, T: AsHandle> {
     pub(crate) lock: &'lock mut RwLock<T>,
 }
 
-impl<T: AsRawHandle> ops::Deref for RwLockWriteGuard<'_, T> {
+impl<T: AsHandle> ops::Deref for RwLockWriteGuard<'_, T> {
     type Target = T;
 
     #[inline]
@@ -20,17 +21,17 @@ impl<T: AsRawHandle> ops::Deref for RwLockWriteGuard<'_, T> {
     }
 }
 
-impl<T: AsRawHandle> ops::DerefMut for RwLockWriteGuard<'_, T> {
+impl<T: AsHandle> ops::DerefMut for RwLockWriteGuard<'_, T> {
     #[inline]
     fn deref_mut(&mut self) -> &mut Self::Target {
         &mut self.lock.inner
     }
 }
 
-impl<T: AsRawHandle> Drop for RwLockWriteGuard<'_, T> {
+impl<T: AsHandle> Drop for RwLockWriteGuard<'_, T> {
     #[inline]
     fn drop(&mut self) {
-        let handle = self.lock.inner.as_raw_handle();
+        let handle = self.lock.inner.as_handle().as_raw_handle();
         syscall(unsafe { UnlockFile(handle, 0, 0, 1, 0) })
             .expect("Could not unlock the file descriptor");
     }