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task_list.md

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Tasks that Saprot potentially supports


Overview

Content


Protein-Level classification

  1. Fold Class Prediction
  2. Localization Prediction
  3. Function Prediction
  4. Subcellular Localization
  5. Domain Classification
  6. Membrane Protein Classification
  7. Enzyme Classification
  8. Post-translational Modification Site Classification
  9. Protein Stability Classification
  10. Protein Solubility Classification
  11. Antigenicity Classification
  12. Protein Aggregation Classification
  13. Protein Family Classification
  14. Protein Structural Class Prediction
  15. Protein Subunit Interface Classification
  16. Protein Motif Classification
  17. Protein Epitope Classification
  18. Protein Interaction Network Classification
  19. Protein Toxicity Classification
  20. Protein Expression Level Classification
  21. Protein Dynamics Classification
  22. Protein Flexibility Classification
  23. Protein Function Annotation
  24. Protein Interaction Type Classification
  25. Protein Disease Association Classification
  26. Protein Functional Domain Classification

Protein-level regression tasks

  1. Thermal Stability Prediction
  2. Fluorescence Intensity Prediction
  3. Binding Affinity Prediction
  4. Solubility Prediction
  5. Expression Level Prediction
  6. Enzymatic Activity Prediction
  7. Hydrophobicity Prediction
  8. Protease Sensitivity Prediction
  9. Protein Interaction Strength Prediction
  10. Drug Binding Affinity Prediction
  11. Protein Stability Change upon Mutation Prediction
  12. Protein Ligand Binding Kinetics Prediction
  13. Protein Stability in Different Temperatures Prediction
  14. Protein Stability in Different Solvents Prediction

Protein-protein classification

  1. Protein-Protein Interaction (PPI) Prediction
  2. Interaction Type Classification
  3. Disease-Associated Interaction Prediction
  4. Mutational Impact Classification
  5. Functional Annotation Classification
  6. Interaction Network Module Detection
  7. Interaction Stability Prediction

Protein-protein Regression

  1. Interaction Strength Prediction
  2. Binding Free Energy Calculation
  3. Interaction Affinity Prediction
  4. Mutational Impact Quantification
  5. Interaction Kinetics Prediction

Zero-shot mutation Effect prediction

  1. Enzyme Activity Prediction
  2. Virus Fitness Prediction
  3. Driver Mutation Prediction
  4. Protein Stability Prediction
  5. Immune Escape Prediction
  6. MHC Binding Prediction
  7. Pathogenicity Prediction
  8. Membrane Protein Function Prediction
  9. Functional Domain Impact Prediction

Protein sequence design

  1. Enzyme Function Optimization
  2. Protein Stability Enhancement
  3. Protein Folding Prediction
  4. Antibody Design
  5. Development of Novel Protein Drugs
  6. Vaccine Design
  7. Protein Engineering
  8. Synthetic Antibody Fragments Design

Residue-level Classification

  1. Secondary Structure Prediction
  2. Binding Site Prediction
  3. Active Site Prediction
  4. Post-Translational Modification (PTM) Site Prediction
  5. Mutation Impact Prediction
  6. Transmembrane Region Prediction
  7. Conservation Score Prediction
  8. Interface Residue Prediction
  9. Enzyme Binding Site Prediction
  10. Metal Binding Site Prediction
  11. Disease-Associated Variant Prediction
  12. Immune Receptor Binding Prediction
  13. Glycosylation Site Prediction