diff --git a/.github/workflows/mediasoup-worker-fuzzer.yaml b/.github/workflows/mediasoup-worker-fuzzer.yaml
index 5f4e5d953e..211754342f 100644
--- a/.github/workflows/mediasoup-worker-fuzzer.yaml
+++ b/.github/workflows/mediasoup-worker-fuzzer.yaml
@@ -37,4 +37,6 @@ jobs:
       - name: invoke -r worker fuzzer
         run: invoke -r worker fuzzer
 
-      # We don't run mediasoup-worker-fuzzer (maybe in the future).
+      # Run mediasoup-worker-fuzzer for 5 minutes.
+      - name: run-fuzzer.sh 300
+        run: cd worker && ./scripts/run-fuzzer.sh 300
diff --git a/worker/Dockerfile b/worker/Dockerfile
index 64ae430df2..674291f118 100644
--- a/worker/Dockerfile
+++ b/worker/Dockerfile
@@ -28,6 +28,9 @@ ENV CXX="clang++"
 
 ENV MEDIASOUP_LOCAL_DEV="true"
 ENV KEEP_BUILD_ARTIFACTS="1"
+# Disable liburing due to this bug:
+# https://github.com/versatica/mediasoup/issues/1334
+ENV MESON_ARGS="-Dms_disable_liburing=true"
 
 WORKDIR /mediasoup
 
diff --git a/worker/Dockerfile.alpine b/worker/Dockerfile.alpine
index 68cf11664d..04689b61f0 100644
--- a/worker/Dockerfile.alpine
+++ b/worker/Dockerfile.alpine
@@ -11,6 +11,9 @@ ENV CXX="g++"
 
 ENV MEDIASOUP_LOCAL_DEV="true"
 ENV KEEP_BUILD_ARTIFACTS="1"
+# Disable liburing due to this bug:
+# https://github.com/versatica/mediasoup/issues/1334
+ENV MESON_ARGS="-Dms_disable_liburing=true"
 
 WORKDIR /mediasoup
 
diff --git a/worker/scripts/run-fuzzer.sh b/worker/scripts/run-fuzzer.sh
new file mode 100755
index 0000000000..bc9c5321b6
--- /dev/null
+++ b/worker/scripts/run-fuzzer.sh
@@ -0,0 +1,38 @@
+#!/usr/bin/env bash
+
+WORKER_PWD=${PWD}
+DURATION_SEC=$1
+
+current_dir_name=${WORKER_PWD##*/}
+if [ "${current_dir_name}" != "worker" ] ; then
+	echo "run-fuzzer.sh [ERROR] $(basename $0) must be called from mediasoup/worker directory" >&2
+	exit 1
+fi
+
+if [ "$#" -eq 0 ] ; then
+	echo "run-fuzzer.sh [ERROR] duration (in seconds) must be fiven as argument" >&2
+	exit 1
+fi
+
+invoke fuzzer-run-all &
+
+MEDIASOUP_WORKER_FUZZER_PID=$!
+
+i=${DURATION_SEC}
+
+until [ ${i} -eq 0 ]
+do
+	echo "run-fuzzer.sh [INFO] ${i} seconds left"
+	if ! kill -0 ${MEDIASOUP_WORKER_FUZZER_PID} &> /dev/null ; then
+		echo "run-fuzzer.sh [ERROR] mediasoup-worker-fuzzer died" >&2
+		exit 1
+	else
+		((i=i-1))
+		sleep 1
+	fi
+done
+
+echo "run-fuzzer.sh [INFO] mediasoup-worker-fuzzer is still running after given ${DURATION_SEC} seconds so no fuzzer issues so far"
+
+kill -SIGTERM ${MEDIASOUP_WORKER_FUZZER_PID} &> /dev/null
+exit 0
diff --git a/worker/tasks.py b/worker/tasks.py
index a99f74cf5c..728e7cf962 100644
--- a/worker/tasks.py
+++ b/worker/tasks.py
@@ -23,7 +23,7 @@
 import inspect;
 import shutil;
 # We import this from a custom location and pylint doesn't know.
-from invoke import task; # pylint: disable=import-error
+from invoke import task, call; # pylint: disable=import-error
 
 MEDIASOUP_BUILDTYPE = os.getenv('MEDIASOUP_BUILDTYPE') or 'Release';
 WORKER_DIR = os.path.dirname(os.path.abspath(
@@ -135,14 +135,14 @@ def meson_ninja(ctx):
 
 
 @task(pre=[meson_ninja])
-def setup(ctx):
+def setup(ctx, meson_args=MESON_ARGS):
     """
     Run meson setup
     """
     if MEDIASOUP_BUILDTYPE == 'Release':
         with ctx.cd(f'"{WORKER_DIR}"'):
             ctx.run(
-                f'"{MESON}" setup --prefix "{MEDIASOUP_INSTALL_DIR}" --bindir "" --libdir "" --buildtype release -Db_ndebug=true {MESON_ARGS} "{BUILD_DIR}"',
+                f'"{MESON}" setup --prefix "{MEDIASOUP_INSTALL_DIR}" --bindir "" --libdir "" --buildtype release -Db_ndebug=true {meson_args} "{BUILD_DIR}"',
                 echo=True,
                 pty=PTY_SUPPORTED,
                 shell=SHELL
@@ -150,7 +150,7 @@ def setup(ctx):
     elif MEDIASOUP_BUILDTYPE == 'Debug':
         with ctx.cd(f'"{WORKER_DIR}"'):
             ctx.run(
-                f'"{MESON}" setup --prefix "{MEDIASOUP_INSTALL_DIR}" --bindir "" --libdir "" --buildtype debug {MESON_ARGS} "{BUILD_DIR}"',
+                f'"{MESON}" setup --prefix "{MEDIASOUP_INSTALL_DIR}" --bindir "" --libdir "" --buildtype debug {meson_args} "{BUILD_DIR}"',
                 echo=True,
                 pty=PTY_SUPPORTED,
                 shell=SHELL
@@ -158,7 +158,7 @@ def setup(ctx):
     else:
         with ctx.cd(f'"{WORKER_DIR}"'):
             ctx.run(
-                f'"{MESON}" setup --prefix "{MEDIASOUP_INSTALL_DIR}" --bindir "" --libdir "" --buildtype {MEDIASOUP_BUILDTYPE} -Db_ndebug=if-release {MESON_ARGS} "{BUILD_DIR}"',
+                f'"{MESON}" setup --prefix "{MEDIASOUP_INSTALL_DIR}" --bindir "" --libdir "" --buildtype {MEDIASOUP_BUILDTYPE} -Db_ndebug=if-release {meson_args} "{BUILD_DIR}"',
                 echo=True,
                 pty=PTY_SUPPORTED,
                 shell=SHELL
@@ -464,11 +464,15 @@ def tidy(ctx):
         );
 
 
-@task(pre=[setup, flatc])
+@task(pre=[call(setup, meson_args=MESON_ARGS + ' -Db_sanitize=address'), flatc])
 def fuzzer(ctx):
     """
     Build the mediasoup-worker-fuzzer binary (which uses libFuzzer)
     """
+
+    # NOTE: We need to pass '-Db_sanitize=address' to enable fuzzer in all Meson
+    # subprojects, so we pass it to the setup() task.
+
     with ctx.cd(f'"{WORKER_DIR}"'):
         ctx.run(
             f'"{MESON}" compile -C "{BUILD_DIR}" -j {NUM_CORES} mediasoup-worker-fuzzer',