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TrinklEtal_Bibliography.ris
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TY - JOUR
AD - Department of Anaesthesia, Narayana Nethralaya, NN-2, Narayana Health City, Bommasandra, Bengaluru, Karnataka, India.
AN - 38025565
AU - Subramanian, S.
AU - Shetty, D.
C1 - There are no conflicts of interest.
C2 - PMC10661646
DA - Jul-Sep
DO - 10.4103/joacp.joacp_440_21
ET - 20230608
IS - 3
N1 - Subramanian, Shalini
Shetty, Deepa
eng
India
2023/11/29
J Anaesthesiol Clin Pharmacol. 2023 Jul-Sep;39(3):499-500. doi: 10.4103/joacp.joacp_440_21. Epub 2023 Jun 8.
PY - 2023
SN - 0970-9185 (Print)
2231-2730 (Electronic)
0970-9185 (Linking)
SP - 499-500
ST - Stifling the sneeze in ACHOO syndrome-What the anesthesiologist should know
T2 - J Anaesthesiol Clin Pharmacol
TI - Stifling the sneeze in ACHOO syndrome-What the anesthesiologist should know
UR - https://www.ncbi.nlm.nih.gov/pubmed/38025565
VL - 39
ID - 164
ER -
TY - JOUR
AB - Two recent studies of eye closure triggered by intense luminance increase suggest that this behavior reflects the melanopsin-based retinal activity known to underlie photophobia, the pathological aversion to light (Kardon, 2012; Kaiser et al., 2021). Early studies of the photic blink reflex (PBR) are reviewed to help guide future research on this possible objective index of photophobia. Electromyographic recordings of the lid-closure muscle, orbicularis oculi, reveal distinct bursts with typical onset latencies of 50 and 80 ms, R50 and R80, respectively. The latter component appears to be especially sensitive to visual signals from intrinsically photosensitive retinal ganglion cells (ipRGCs) and to prior trigeminal nociceptive stimuli. The authors argue that the R80's function, in addition to protecting the eyeballs from physical contact, is to shape the upper and lower eyelids into a narrow slit to restrict incoming light. This serves to prevent retinal bleaching or injury, while allowing continued visual function.
AD - Department of Psychological Sciences, University of Missouri, Columbia, USA. Electronic address: [email protected].
Department of Ophthalmology, Warren Alpert Medical School of Brown University, USA.
AN - 37757999
AU - Hackley, S. A.
AU - Johnson, L. N.
C1 - Declaration of Competing Interest The authors declare that they have no known conflicts of interest to disclose.
DA - Nov
DO - 10.1016/j.biopsycho.2023.108695
ET - 20230925
KW - Humans
*Photophobia
Photic Stimulation
*Blinking
Retinal Ganglion Cells/physiology
Sensation
Reflex, Pupillary/physiology
Intrinsically photosensitive retinal ganglion cells (ipRGCs)
Migraine headache
Photic blink reflex
Photophobia
Pupillary light reflex
N1 - Hackley, Steven A
Johnson, Lenworth N
eng
Review
Netherlands
2023/09/28
Biol Psychol. 2023 Nov;184:108695. doi: 10.1016/j.biopsycho.2023.108695. Epub 2023 Sep 25.
PY - 2023
SN - 1873-6246 (Electronic)
0301-0511 (Linking)
SP - 108695
ST - The photic blink reflex as an index of photophobia
T2 - Biol Psychol
TI - The photic blink reflex as an index of photophobia
UR - https://www.ncbi.nlm.nih.gov/pubmed/37757999
VL - 184
ID - 169
ER -
TY - JOUR
AB - Sneezing is a poorly understood, protective reflex response. It's characterized by the following sequence: eye closure, inspiration, glottic closure, forced expiration with sudden glottic opening, and release of an elevated intrathoracic pressure creating a flow of explosive air through the nose.(1) Studies have indicated an anatomic sneezing area of the brainstem corresponding to the central recipient zone of the nasal sensory neurons in the lateral medulla.(2) The traditional pathophysiology of the sneeze is thought to begin by stimulation of the distal branches of the trigeminal nerve within the nasal mucosa. Afferent neural stimuli are transmitted to the trigeminal ganglion and then the lateral medulla. The efferent phase then begins, giving rise to the sneezing sequence described earlier.(1) In addition to direct nasal irritation, sneezing has been shown to be triggered by several other causes (Table 1). This suggests that alternative mechanisms of sneeze induction other than direct nasal stimulation exist. We report a case of a 34-year-old man undergoing an awake craniotomy for a recurrent World Health Organization grade 2 oligodendroglioma (IDH-mutant, 1p19q-codeleted, ATRX preserved). During the operation we elicited a sneeze response on 3 occasions on stimulation of the olfactory nerve (Video 1). Although we cannot completely exclude costimulation of the sensory trigeminal terminations in the anterior fossa floor, the actual sneezing occurred during tumor peeling away from the arachnoid surface overlaying the olfactory nerve. This suggests a potential accessory route of sneeze stimulation involving the olfactory nerve distinct from the previously described trigemino-related, autonomic (sympathetic and parasympathetic systems) and psychogenic etiologies.
AD - Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, England. Electronic address: [email protected].
Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, England.
AN - 34990839
AU - Sangha, M. S.
AU - Rajwani, K. M.
AU - Pescador, A. M.
AU - Ashkan, K.
AU - Vergani, F.
AU - Bhangoo, R.
AU - Lavrador, J. P.
DA - Mar
DO - 10.1016/j.wneu.2021.12.107
ET - 20220103
KW - Adult
Brain Stem
Humans
Male
Nasal Mucosa
Neoplasm Recurrence, Local
*Olfactory Nerve
*Sneezing/physiology
Trigeminal Nerve/physiology/surgery
Cranial fossa floor
Olfactory nerve
Sneeze
N1 - Sangha, Miljyot Singh
Rajwani, Kapil Mohan
Pescador, Ana Mirallave
Ashkan, Keyoumars
Vergani, Francesco
Bhangoo, Ranjeev
Lavrador, Jose Pedro
eng
Case Reports
Video-Audio Media
2022/01/07
World Neurosurg. 2022 Mar;159:134-135. doi: 10.1016/j.wneu.2021.12.107. Epub 2022 Jan 3.
PY - 2022
SN - 1878-8769 (Electronic)
1878-8750 (Linking)
SP - 134-135
ST - Intraoperative Sneezing Secondary to Indirect Olfactory Nerve Stimulation
T2 - World Neurosurg
TI - Intraoperative Sneezing Secondary to Indirect Olfactory Nerve Stimulation
UR - https://www.ncbi.nlm.nih.gov/pubmed/34990839
VL - 159
ID - 168
ER -
TY - JOUR
AD - University of New South Wales, Sydney, Australia.
Department of Ophthalmology, Prince of Wales Hospital, Sydney. Australia.
University of Notre Dame, Sydney, Australia.
Royal North Shore Hospital, Sydney, Australia.
AN - 33470289
AU - Ting, E. R.
AU - Wong, E. L. S.
AU - Lin, M.
AU - Blah, T.
AU - Huang, J.
AU - Goswami, P.
AU - Yang, Y.
AU - Khan, M. A.
AU - Lim, Z. W.
AU - Agar, A.
AU - Francis, I. C.
DA - Nov-Dec
DO - 10.5935/0004-2749.20200112
IS - 6
KW - COVID-19/*prevention & control/*transmission
Facial Muscles
Humans
Lip
*Pressure
*Sneezing
N1 - Ting, Eugene R
Wong, Elizabeth L S
Lin, Michael
Blah, Tyler
Huang, Jessica
Goswami, Pragya
Yang, Yi
Khan, Muhammad A
Lim, Zhi Wei
Agar, Ashish
Francis, Ian C
eng
Letter
Brazil
2021/01/21
Arq Bras Oftalmol. 2020 Nov-Dec;83(6):569-570. doi: 10.5935/0004-2749.20200112.
PY - 2020
SN - 1678-2925 (Electronic)
0004-2749 (Linking)
SP - 569-570
ST - Utilization of the philtral pressure technique as an efficacious measure to prevent coronavirus transmission through sneezing
T2 - Arq Bras Oftalmol
TI - Utilization of the philtral pressure technique as an efficacious measure to prevent coronavirus transmission through sneezing
UR - https://www.ncbi.nlm.nih.gov/pubmed/33470289
VL - 83
ID - 167
ER -
TY - JOUR
AD - Department of Biological and Environmental Sciences, Longwood University, Farmville, VA 23909.
AN - 33294096
AU - Shanle, E. K.
AU - Trubitsyn, D.
C2 - PMC7669283
DO - 10.1128/jmbe.v21i3.2173
ET - 20201112
IS - 3
N1 - Shanle, Erin K
Trubitsyn, Denis
eng
2020/12/10
J Microbiol Biol Educ. 2020 Nov 12;21(3):21.3.70. doi: 10.1128/jmbe.v21i3.2173. eCollection 2020.
PY - 2020
SN - 1935-7877 (Print)
1935-7885 (Electronic)
1935-7877 (Linking)
ST - A Student-Focused Lab Module To Investigate Single-Nucleotide Polymorphisms of Common Heritable Traits
T2 - J Microbiol Biol Educ
TI - A Student-Focused Lab Module To Investigate Single-Nucleotide Polymorphisms of Common Heritable Traits
UR - https://www.ncbi.nlm.nih.gov/pubmed/33294096
VL - 21
ID - 170
ER -
TY - JOUR
AD - Department of Ophthalmology, Columbia University Irving Medical Center, New York, New York.
AN - 31609836
AU - Scherbakova, I.
AU - Casper, D. S.
AU - Bearelly, S.
AU - Odel, J. G.
DA - Jun
DO - 10.1097/WNO.0000000000000851
ET - 2019/10/15
IS - 2
N1 - Scherbakova, Ioana
Casper, Daniel S
Bearelly, Srilaxmi
Odel, Jeffrey G
eng
J Neuroophthalmol. 2020 Jun;40(2):243-245. doi: 10.1097/WNO.0000000000000851.
PY - 2020
SN - 1536-5166 (Electronic)
1070-8022 (Linking)
SP - 243-245
ST - Acute Solar Retinopathy and the Autosomal Dominant Compelling Helio-Ophthalmic Outburst Syndrome
T2 - J Neuroophthalmol
TI - Acute Solar Retinopathy and the Autosomal Dominant Compelling Helio-Ophthalmic Outburst Syndrome
UR - https://www.ncbi.nlm.nih.gov/pubmed/31609836
VL - 40
ID - 131
ER -
TY - JOUR
AB - Second only to headache, photophobia is the most debilitating symptom reported by people with migraine. While the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to play a role, how cone and melanopsin signals are integrated in this pathway to produce visual discomfort is poorly understood. We studied 60 people: 20 without headache and 20 each with interictal photophobia from migraine with or without visual aura. Participants viewed pulses of spectral change that selectively targeted melanopsin, the cones, or both and rated the degree of visual discomfort produced by these stimuli while we recorded pupil responses. We examined the data within a model that describes how cone and melanopsin signals are weighted and combined at the level of the retina and how this combined signal is transformed into a rating of discomfort or pupil response. Our results indicate that people with migraine do not differ from headache-free controls in the manner in which melanopsin and cone signals are combined. Instead, people with migraine demonstrate an enhanced response to integrated ipRGC signals for discomfort. This effect of migraine is selective for ratings of visual discomfort, in that an enhancement of pupil responses was not seen in the migraine group, nor were group differences found in surveys of other behaviors putatively linked to ipRGC function (chronotype, seasonal sensitivity, presence of a photic sneeze reflex). By revealing a dissociation in the amplification of discomfort vs. pupil response, our findings suggest a postretinal alteration in processing of ipRGC signals for photophobia in migraine.
AD - Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104.
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; [email protected].
AN - 32632006
AU - McAdams, H.
AU - Kaiser, E. A.
AU - Igdalova, A.
AU - Haggerty, E. B.
AU - Cucchiara, B.
AU - Brainard, D. H.
AU - Aguirre, G. K.
C2 - PMC7382295
DA - Jul 21
DO - 10.1073/pnas.2007402117
ET - 2020/07/08
IS - 29
KW - Adult
Female
Humans
Male
Migraine Disorders/*metabolism
Photic Stimulation
Photophobia/*metabolism
Pupil/physiology
Retinal Cone Photoreceptor Cells/physiology
Retinal Ganglion Cells/*physiology
Rod Opsins/physiology
*ipRGCs
*melanopsin
*migraine
*photophobia
with Alder Biopharmaceuticals. The remaining authors declare that they have no
relevant financial interests that relate to the research described in this paper.
N1 - McAdams, Harrison
Kaiser, Eric A
Igdalova, Aleksandra
Haggerty, Edda B
Cucchiara, Brett
Brainard, David H
Aguirre, Geoffrey K
eng
P30 EY001583/EY/NEI NIH HHS/
R01 EY024681/EY/NEI NIH HHS/
R25 NS065745/NS/NINDS NIH HHS/
T32 AG000255/AG/NIA NIH HHS/
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17320-17329. doi: 10.1073/pnas.2007402117. Epub 2020 Jul 6.
PY - 2020
SN - 1091-6490 (Electronic)
0027-8424 (Linking)
SP - 17320-17329
ST - Selective amplification of ipRGC signals accounts for interictal photophobia in migraine
T2 - Proc Natl Acad Sci U S A
TI - Selective amplification of ipRGC signals accounts for interictal photophobia in migraine
UR - https://www.ncbi.nlm.nih.gov/pubmed/32632006
VL - 117
ID - 136
ER -
TY - JOUR
AB - PURPOSE: To evaluate the efficacy of slit lamp breath shields to prevent droplet spray from a simulated sneeze. DESIGN: Experimental study to test effectiveness of personal protective equipment. METHODS: The nozzle of a spray gun was adjusted to angularly disperse a mist of colored dye that approximated a patient sneezing on a dimensionally accurate cardboard slit lamp model. We tested the designs of six commercially available breath shields, and one breath shield repurposed from a plastic container lid. Each breath shield was sprayed in a standardized fashion three times and the amount of overspray compared with no shield was quantified. The surface area that was sprayed was calculated using Adobe Photoshop's color range function. The average percentage of overspray of each breath shield was computed in comparison to the control. RESULTS: The breath shields ranged in surface area from 116-1254 cm(2) and the amount of overspray varied from 54% to virtually none. Larger breath shields offered better protection than smaller ones. Breath shields attached to the objective lens arm were a better barrier than those hung by the oculars of comparable size. A repurposed plastic lid breath shield was 513cm(2), was slightly curved toward the examiner's face, and allowed only 2% overspray. The largest breath shield (1254 cm(2)) hung near the oculars and prevented essentially all the overspray. CONCLUSION: The performance of different designs of breath shields is variable. Even high functioning shields should be used in conjunction with personal protective equipment including masks, goggles and gloves, and handwashing. Ideally patients should also wear a cloth mask during all slit lamp exams.
AD - Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada;. Electronic address: [email protected].
Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Department of Ophthalmology & Vision Sciences, University of Toronto, Toronto, ON, Canada.
AN - 32407727
AU - Liu, J.
AU - Wang, A. Y.
AU - Ing, E. B.
C2 - PMC7212996
DA - May 11
DO - 10.1016/j.ajo.2020.05.005
ET - 2020/05/15
N1 - Liu, John
Wang, Annie Y
Ing, Edsel B
eng
Am J Ophthalmol. 2020 May 11. pii: S0002-9394(20)30234-8. doi: 10.1016/j.ajo.2020.05.005.
PY - 2020
SN - 1879-1891 (Electronic)
0002-9394 (Linking)
ST - Efficacy of slit lamp breath shields
T2 - Am J Ophthalmol
TI - Efficacy of slit lamp breath shields
UR - https://www.ncbi.nlm.nih.gov/pubmed/32407727
ID - 132
ER -
TY - JOUR
AD - Department of Anaesthesiology, Medical Research Foundation, Sankara Nethralaya, 41/18, College Road, Nungambakkam, Chennai, Tamil Nadu, India. [email protected].
Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, 41/18, College Road, Nungambakkam, Chennai, Tamil Nadu, India.
AN - 32546750
AU - Jaichandran, V. V.
AU - Raman, R.
C2 - PMC7296523
DA - Jun 16
DO - 10.1038/s41433-020-1027-5
ET - 2020/06/18
N1 - Jaichandran, V V
Raman, Rajiv
eng
England
Eye (Lond). 2020 Jun 16. pii: 10.1038/s41433-020-1027-5. doi: 10.1038/s41433-020-1027-5.
PY - 2020
SN - 1476-5454 (Electronic)
0950-222X (Linking)
ST - Aerosol prevention box for regional anaesthesia for eye surgery in COVID times
T2 - Eye (Lond)
TI - Aerosol prevention box for regional anaesthesia for eye surgery in COVID times
UR - https://www.ncbi.nlm.nih.gov/pubmed/32546750
ID - 133
ER -
TY - JOUR
AB - Photic sneeze reflex (PSR) is an interesting but yet mysterious phenotype featured by individuals' response of sneezing in exposure to bright light. To uncover the underlying genetic markers (single nucleotide polymorphisms, SNPs), a genome-wide association study (GWAS) was conducted exclusively in a Chinese population of 3417 individuals (PSR prevalence at 25.6%), and reproducibly identified both a replicative rs10427255 on 2q22.3 and a novel locus of rs1032507 on 3p12.1 in various effect models (additive, as well as dominant and recessive). Minor alleles respectively contributed to increased or reduced risk for PSR with odds ratio (95% confidence interval) at 1.68 ([1.50, 1.88]) for rs10427255 and 0.65 ([0.58, 0.72]) for rs1032507. The two independent SNPs were intergenic, and collectively enhanced PSR classification by lifting the area-under-curve value in ROC curve to 0.657. Together with previous GWAS in other populations, the result substantiated the polygenic and non-ethnicity-specific nature behind the PSR phenotype.
AD - Department of Epidemiology and Biostatistics, West China School of Public Health, Sichuan University, Renmin South Road 16, Chengdu, Sichuan Province, 610041, P.R. China. [email protected].
Chengdu 23Mofang Biotechnology Co., Ltd., High-tech District E6-10, Chengdu, Sichuan Province, 610042, P.R. China.
Department of Epidemiology and Biostatistics, West China School of Public Health, Sichuan University, Renmin South Road 16, Chengdu, Sichuan Province, 610041, P.R. China.
AN - 30899065
AU - Wang, M.
AU - Sun, X.
AU - Shi, Y.
AU - Song, X.
AU - Mi, H.
C2 - PMC6428856
DA - Mar 21
DO - 10.1038/s41598-019-41551-0
ET - 2019/03/23
IS - 1
N1 - Wang, Mengqiao
Sun, Xinghan
Shi, Yang
Song, Xiaojun
Mi, Hao
eng
20822041B4081/Sichuan University (SCU)
20822041B4009/Sichuan University (SCU)
England
Sci Rep. 2019 Mar 21;9(1):4993. doi: 10.1038/s41598-019-41551-0.
PY - 2019
SN - 2045-2322 (Electronic)
2045-2322 (Linking)
SP - 4993
ST - A genome-wide association study on photic sneeze reflex in the Chinese population
T2 - Sci Rep
TI - A genome-wide association study on photic sneeze reflex in the Chinese population
UR - https://www.ncbi.nlm.nih.gov/pubmed/30899065
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428856/pdf/41598_2019_Article_41551.pdf
VL - 9
ID - 125
ER -
TY - JOUR
AB - BACKGROUND: Sneezing is an almost universal daily phenomenon as a reflex to evacuate irritants from the nasal cavities. An autonomic-controlled buildup of intrathoracic pressure against a closed glottis followed by sudden release results in a burst of 1 kPa of air through the upper airway. Active intervention to limit a sneeze can be deleterious. Closure of the airway during a sneeze can result in over 20 times the airway pressures resulting in a variety of untoward events. This review summarizes all reported injuries that occurred as the result of a sneeze. OBJECTIVE: The objective of this review is to summarize the risks of closed-airway sneezing and determine if there are any trends which can help understand such injuries. METHODS: A comprehensive literature review was performed from 1948 to 2018 to identify all reports of sneeze-related injuries. Information was compiled from reports to gain insights into comorbidities and risk factors for sneeze injuries. RESULTS: There were 52 unique reports of sneeze-related injuries in the literature that were categorized into 6 areas of injury: intrathoracic, laryngeal/pharyngeal, ocular/orbital, intracranial/neurological, otologic, and other. The mean age of subjects who suffered a sneeze injury was 40 years old (range: 15-84 years), with 81% being male gender. Thirty percent had a risk factor for injury of prior trauma (5) or respiratory compromise (5). CONCLUSION: A variety of injuries can occur during a sneeze, especially when a closed-airway sneeze is attempted, and high Valsalva pressure is transmitted to the other systems. Men are more at risk for these injuries with the majority occurring in patients with no known risk factor. When triggered, a sneeze should be allowed to proceed without intervention to prevent associated injuries.
AD - 1 Department of Otolaryngology - Head and Neck Surgery, Boston University School of Medicine, Boston, Massachusetts.
AN - 30616365
AU - Setzen, S.
AU - Platt, M.
DA - May
DO - 10.1177/1945892418823147
ET - 2019/01/09
IS - 3
KW - Humans
Risk Factors
*Sneezing/physiology
Valsalva Maneuver/physiology
Wounds and Injuries/*etiology
Valsalva
airway
injury
sneeze
sneezing
trauma
N1 - Setzen, Sean
Platt, Michael
eng
Review
Am J Rhinol Allergy. 2019 May;33(3):331-337. doi: 10.1177/1945892418823147. Epub 2019 Jan 8.
PY - 2019
SN - 1945-8932 (Electronic)
1945-8932 (Linking)
SP - 331-337
ST - The Dangers of Sneezing: A Review of Injuries
T2 - Am J Rhinol Allergy
TI - The Dangers of Sneezing: A Review of Injuries
UR - https://www.ncbi.nlm.nih.gov/pubmed/30616365
VL - 33
ID - 153
ER -
TY - JOUR
AB - BACKGROUND: Photic sneeze syndrome (PSS) is a condition that causes sneezing when the eye is exposed to sudden bright light. Because alterations in the parasympathetic and trigeminal nerve systems have been implicated in PSS, and such systems are involved in migraine and stress-related disorders, we examined the possible associations of PSS with migraine and psychological distress. METHODS: The presence of PSS and migraine was examined in 11 840 participants from the general population using a self-report questionnaire. Psychological distress was assessed by the 6-item Kessler Psychological Distress Scale (K6). RESULTS: The overall prevalence of PSS was 3.1%. Individuals with PSS were more likely to suffer from migraine (odds ratio = 1.97, P = 2.18 x 10(-9) ), clinically relevant psychological distress (K6 score >/= 5: odds ratio = 1.40, P = 0.00143), and severe psychological distress (K6 score >/= 13: odds ratio = 1.49, P = 0.0486). Overall, K6 scores were significantly higher in those with PSS than in those without (P = 0.000013). Analysis controlling for sex and the presence of migraine showed that PSS was associated with higher K6 scores irrespective of sex or the presence of migraine. CONCLUSIONS: The low prevalence of PSS identified in the present study may be due to the inadequate ability of the self-report questionnaire to identify PSS. Despite such limitation, the present study suggests that individuals with PSS are more likely to suffer from migraine and psychological distress than those without PSS. PSS may be a potential target for the research of migraine and stress-related disorders.
AD - Department of Mental Disorder Research, National Center of Neurology and Psychiatry, National Institute of Neuroscience, Kodaira, Japan.
Department of Psychiatry, Shinshu University School of Medicine, Matsumoto, Japan.
Child and Adolescent Developmental Psychiatry, Shinshu University School of Medicine, Matsumoto, Japan.
GeneQuest Inc., Tokyo, Japan.
AN - 31287245
AU - Sasayama, D.
AU - Asano, S.
AU - Nogawa, S.
AU - Takahashi, S.
AU - Saito, K.
AU - Kunugi, H.
DA - Sep
DO - 10.1002/npr2.12067
ET - 2019/07/10
IS - 3
KW - migraine
neuropsychology
photic sneeze reflex
psychological distress
trigeminal nerve
N1 - Sasayama, Daimei
Asano, Shinya
Nogawa, Shun
Takahashi, Shoko
Saito, Kenji
Kunugi, Hiroshi
eng
Genequest Inc.
27-1/NCNP Intramural Research Grant for Neurological and Psychiatric Disorders
Neuropsychopharmacol Rep. 2019 Sep;39(3):217-222. doi: 10.1002/npr2.12067. Epub 2019 Jul 9.
PY - 2019
SN - 2574-173X (Electronic)
2574-173X (Linking)
SP - 217-222
ST - Possible association between photic sneeze syndrome and migraine and psychological distress
T2 - Neuropsychopharmacol Rep
TI - Possible association between photic sneeze syndrome and migraine and psychological distress
UR - https://www.ncbi.nlm.nih.gov/pubmed/31287245
VL - 39
ID - 127
ER -
TY - JOUR
AB - OBJECTIVE: To review clinical and pre-clinical evidence supporting the role of visual pathways, from the eye to the cortex, in the development of photophobia in headache disorders. BACKGROUND: Photophobia is a poorly understood light-induced phenomenon that emerges in a variety of neurological and ophthalmological conditions. Over the years, multiple mechanisms have been proposed to explain its causes; however, scarce research and lack of systematic assessment of photophobia in patients has made the search for answers quite challenging. In the field of headaches, significant progress has been made recently on how specific visual networks contribute to photophobia features such as light-induced intensification of headache, increased perception of brightness and visual discomfort, which are frequently experienced by migraineurs. Such progress improved our understanding of the phenomenon and points to abnormal processing of light by both cone/rod-mediated image-forming and melanopsin-mediated non-image-forming visual pathways, and the consequential transfer of photic signals to multiple brain regions involved in sensory, autonomic and emotional regulation. CONCLUSION: Photophobia phenotype is diverse, and the relative contribution of visual, trigeminal and autonomic systems may depend on the disease it emerges from. In migraine, photophobia could result from photic activation of retina-driven pathways involved in the regulation of homeostasis, making its association with headache more complex than previously thought.
AD - Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Department of Ophthalmology, UCSF School of Medicine, San Francisco, CA, USA.
AN - 29940781
AU - Noseda, R.
AU - Copenhagen, D.
AU - Burstein, R.
C2 - PMC6461529
DA - Nov
DO - 10.1177/0333102418784750
ET - 2018/06/27
IS - 13
KW - Migraine
autonomic
hypothalamus
photoreceptors
retina
thalamus
N1 - Noseda, Rodrigo
Copenhagen, David
Burstein, Rami
eng
R21 NS090254/NS/NINDS NIH HHS/
R01 NS051484/NS/NINDS NIH HHS/
R01 NS069847/NS/NINDS NIH HHS/
R01 NS094198/NS/NINDS NIH HHS/
R37 NS079678/NS/NINDS NIH HHS/
R01 NS104296/NS/NINDS NIH HHS/
England
Cephalalgia. 2019 Nov;39(13):1623-1634. doi: 10.1177/0333102418784750. Epub 2018 Jun 25.
PY - 2019
SN - 1468-2982 (Electronic)
0333-1024 (Linking)
SP - 1623-1634
ST - Current understanding of photophobia, visual networks and headaches
T2 - Cephalalgia
TI - Current understanding of photophobia, visual networks and headaches
UR - https://www.ncbi.nlm.nih.gov/pubmed/29940781
VL - 39
ID - 130
ER -
TY - JOUR
AB - Photophobia may arise from various causes and frequently accompanies numerous ocular diseases. In modern highly illuminated world, complaints about greater photosensitivity to blue light increasingly appear. However, the pathophysiology of photophobia is still debated. In the present work, we investigated in vivo the role of various neural pathways potentially implicated in blue-light aversion. Moreover, we studied the light-induced neuroinflammatory processes on the ocular surface and in the trigeminal pathways. Adult male C57BL/6J mice were exposed either to blue (400-500 nm) or to yellow (530-710 nm) LED light (3 h, 6 mW/cm(2)). Photosensitivity was measured as the time spent in dark or illuminated parts of the cage. Pharmacological treatments were applied: topical instillation of atropine, pilocarpine or oxybuprocaine, intravitreal injection of lidocaine, norepinephrine or "blocker" of the visual photoreceptor transmission, and intraperitoneal injection of a melanopsin antagonist. Clinical evaluations (ocular surface state, corneal mechanical sensitivity and tear quantity) were performed directly after exposure to light and after 3 days of recovery in standard light conditions. Trigeminal ganglia (TGs), brainstems and retinas were dissected out and conditioned for analyses. Mice demonstrated strong aversion to blue but not to yellow light. The only drug that significantly decreased the blue-light aversion was the intraperitoneally injected melanopsin antagonist. After blue-light exposure, dry-eye-related inflammatory signs were observed, notably after 3 days of recovery. In the retina, we observed the increased immunoreactivity for GFAP, ATF3, and Iba1; these data were corroborated by RT-qPCR. Moreover, retinal visual and non-visual photopigments distribution was altered. In the trigeminal pathway, we detected the increased mRNA expression of cFOS and ATF3 as well as alterations in cytokines' levels. Thus, the wavelength-dependent light aversion was mainly mediated by melanopsin-containing cells, most likely in the retina. Other potential pathways of light reception were also discussed. The phototoxic message was transmitted to the trigeminal system, inducing both inflammation at the ocular surface and stress in the retina. Further investigations of retina-TG connections are needed.
AD - R&D, Essilor International, Paris, France.
Sorbonne Universite, Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris, France.
Centre Hospitalier Nationale d'Ophtalmologie des Quinze-Vingts, Paris, France.
CHU Robert Debre, Universite Reims Champagne-Ardenne, Reims, France.
Versailles Saint-Quentin-en-Yvelines Universite, Versailles, France.
AN - 31178682
AU - Marek, V.
AU - Reboussin, E.
AU - Degardin-Chicaud, J.
AU - Charbonnier, A.
AU - Dominguez-Lopez, A.
AU - Villette, T.
AU - Denoyer, A.
AU - Baudouin, C.
AU - Reaux-Le Goazigo, A.
AU - Melik Parsadaniantz, S.
C2 - PMC6543920
DO - 10.3389/fnins.2019.00497
ET - 2019/06/11
KW - blue light
dry eye
melanopsin
neurotoxicity
ocular nociception
photophobia
trigeminal pathway
N1 - Marek, Veronika
Reboussin, Elodie
Degardin-Chicaud, Julie
Charbonnier, Angeline
Dominguez-Lopez, Alfredo
Villette, Thierry
Denoyer, Alexandre
Baudouin, Christophe
Reaux-Le Goazigo, Annabelle
Melik Parsadaniantz, Stephane
eng
Switzerland
Front Neurosci. 2019 May 22;13:497. doi: 10.3389/fnins.2019.00497. eCollection 2019.
PY - 2019
SN - 1662-4548 (Print)
1662-453X (Linking)
SP - 497
ST - Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo
T2 - Front Neurosci
TI - Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo
UR - https://www.ncbi.nlm.nih.gov/pubmed/31178682
VL - 13
ID - 129
ER -
TY - JOUR
AB - Background: The photic sneeze reflex (autosomal dominant) is a condition that causes sneezing in response to numerous stimuli, such as looking at bright lights or periocular (surrounding the eyeball) injection. Unexpected or sudden sneezing during injection can be a dangerous side effect in periocular injection, in which abrupt head movement may cause globe injury. Aims: We intended to evaluate the efficacy of adding fentanyl, dexmedetomidine, and antihistamines on the incidence of the sneeze reflex associated with propofol sedation during periocular local anesthesia injections. Settings and Design: Our study was a randomized, prospective, double-blinded and controlled clinical study. Patients and Methods: This study was conducted in Ain Shams and Fayoum university hospitals at the ophthalmic surgery department. After obtaining approval from our universities ethical committee and written informed valid consents from the patients, 90 patients were included in this study. The study population included patients of both sex, ASA grade 1 and 2, in the age ranging from 18-65 years. Patients were scheduled for cataract extraction surgeries and received peribulbar block. Then patients were randomly divided into three groups (30 patients each) using a computer- generated table of random numbers. Patients were preoxygenated with supplemental oxygen by nasal cannula, all 90 patients received intravenous propofol 1mg.kg- 1 bolus for sedation and were randomized to receive adjunctive drug 2 to 4 minutes prior to propofol injection: 30 patients received intravenous fentanyl 1 mumg.kg(-1) (Group F), 30 patients received dexmedetomidine 1mumg.kg(-1) (Group D), and 30 patients received antihistamine (pheniramine 22.75 mg) (Group H). The same local anesthetic admixture, consisting of 5 mL 2% lidocaine with 90 IU hyaluronidase, combined with 5 mL 0.5% plain bupivacaine in a 10-mL syringe at room temperature was administered to all patients using peribulbar block technique. A masked observer (surgeon or anesthesia assistant) recorded whether the patient had a sneezing event. Continuous cardiorespiratory monitoring was performed intraoperatively. Intraoperative and postoperative medication side effects were recorded including bradycardia (HR <55 beats/min), hypotension (MAP <50 mmHg sustained for >10 min), oxygen desaturation (SpO2<90%), nausea, vomiting and prolonged sedation using Ramsay Sedation Score (RSS). Statistical Analysis Used: Student's t-test and Chi-square test were used for analysis. Results: The demographic data of the three study groups revealed non-significant differences between the three study groups as regards age, sex distribution, and the duration of surgery. No patient was excluded after inclusion to the study. All patients were able to complete the entire study and their data were included in the final analysis. Five events of sneezing had occurred in 90 patients. Two in (D) group and three in (H) group with is no statistically significant difference between the three groups as regard sneezing. Bradycardia, hypotension and sedation had occurred significantly in group (D) compared to group (F) and group (D). No patient suffered from nausea, vomiting or oxygen desaturation in all studied groups. No statistically significant difference as regards patient satisfaction between the three studied groups. Conclusion: Fentanyl, dexmedetomidine and antihistamines with propofol sedation suppress photic sneeze reflex during peribulbar block.
AD - Department of Anesthesia, Ain Shams University, Cairo, Egypt.
Department of Anesthesia, Fayoum University, Faiyum, Egypt.
AN - 31031478
AU - Hakim, K. Y.
AU - Alsaeid, M. A.
C2 - PMC6444960
DA - Jan-Mar
DO - 10.4103/aer.AER_174_18
ET - 2019/04/30
IS - 1
KW - Antihistamines
Fentanyl
dexmedetomidine
peribulbar block
photic sneezing reflex
N1 - Hakim, Karim Yk
Alsaeid, Mohammed Awad
eng
India
Anesth Essays Res. 2019 Jan-Mar;13(1):40-43. doi: 10.4103/aer.AER_174_18.
PY - 2019
SN - 0259-1162 (Print)
2229-7685 (Linking)
SP - 40-43
ST - Comparative Study between the Efficacy of Fentanyl, Antihistamines, and Dexmedetomidine in Suppressing Photic Sneeze Reflex during Peribulbar Block
T2 - Anesth Essays Res
TI - Comparative Study between the Efficacy of Fentanyl, Antihistamines, and Dexmedetomidine in Suppressing Photic Sneeze Reflex during Peribulbar Block
UR - https://www.ncbi.nlm.nih.gov/pubmed/31031478
http://www.aeronline.org/article.asp?issn=0259-1162;year=2019;volume=13;issue=1;spage=40;epage=43;aulast=Hakim
VL - 13
ID - 124
ER -
TY - JOUR
AU - Fougere, Édouard
DO - 10.1016/j.actpha.2019.01.011
IS - 584
PY - 2019
SE - 12
SN - 05153700
SP - 12-13
ST - On vous demande, sachez répondre
T2 - Actualités Pharmaceutiques
TI - On vous demande, sachez répondre
VL - 58
ID - 156
ER -
TY - JOUR
AD - Westmead Hospital, Westmead, Sydney, Australia. [email protected].
University of New South Wales, Kensington, Sydney, Australia.
Nepean Hospital, Nepean, Sydney, Australia.
Department of Ophthalmology, Prince of Wales Hospital, Randwick, Sydney, Australia.
AN - 30783255
AU - Bobba, S.
AU - Spencer, S. K. R.
AU - Fox, O. J. K.
AU - Agar, A.
AU - Coroneo, M. T.
AU - Francis, I. C.
DA - Feb 19
DO - 10.1038/s41433-019-0368-4
ET - 2019/02/21
N1 - Bobba, Samantha
Spencer, Sascha K R
Fox, Olivia J K
Agar, Ashish
Coroneo, Minas T
Francis, Ian C
eng
Letter
England
Eye (Lond). 2019 Feb 19. pii: 10.1038/s41433-019-0368-4. doi: 10.1038/s41433-019-0368-4.
PY - 2019
SN - 1476-5454 (Electronic)
0950-222X (Linking)
ST - Management of the photic sneeze reflex utilising the philtral pressure technique
T2 - Eye (Lond)
TI - Management of the photic sneeze reflex utilising the philtral pressure technique
UR - https://www.ncbi.nlm.nih.gov/pubmed/30783255
https://www.nature.com/articles/s41433-019-0368-4.pdf
ID - 126
ER -
TY - JOUR
AB - The human pupillary light response is driven by all classes of photoreceptors in the human eye-the three classes of cones, the rods, and the intrinsically photosensitive retinal ganglion cells (ipRGCs) expressing the photopigment melanopsin. These photoreceptor classes have distinct but overlapping spectral tuning, and even a monochromatic light with a wavelength matched to the peak spectral sensitivity of a given photoreceptor will stimulate all photoreceptors. The method of silent substitution uses pairs of lights ("metamers") to selectively stimulate a given class of photoreceptors while keeping the activation of all others constant. In this primer, we describe the method of silent substitution and provide an overview of studies that have used it to examine inputs to the human pupillary light response.
AD - Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom.
Chronobiology Unit, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, Netherlands.
AN - 30538662
AU - Spitschan, M.
AU - Woelders, T.
C2 - PMC6277556
DO - 10.3389/fneur.2018.00941
ET - 2018/12/13
KW - color vision
ipRGC (intrinsically photosensitive retinal ganglion cell)
melanopsin
metamers
pupil
pupillometry
silent substitution
N1 - Spitschan, Manuel
Woelders, Tom
eng
204686/Wellcome Trust/United Kingdom
Switzerland
Front Neurol. 2018 Nov 27;9:941. doi: 10.3389/fneur.2018.00941. eCollection 2018.
PY - 2018
SN - 1664-2295 (Print)
1664-2295 (Linking)
SP - 941
ST - The Method of Silent Substitution for Examining Melanopsin Contributions to Pupil Control
T2 - Front Neurol
TI - The Method of Silent Substitution for Examining Melanopsin Contributions to Pupil Control
UR - https://www.ncbi.nlm.nih.gov/pubmed/30538662
VL - 9
ID - 139
ER -
TY - JOUR
AB - Photic sneeze syndrome (PSS) is characterized by a tendency to sneeze when the eye is exposed to bright light. Recent genome-wide association studies (GWASs) have identified single-nucleotide polymorphisms (SNPs) associated with PSS in Caucasian populations. We performed a GWAS on PSS in Japanese individuals who responded to a web-based survey and provided saliva samples. After quality control, genotype data of 210,086 SNPs in 11,409 individuals were analyzed. The overall prevalence of PSS was 3.2%. Consistent with previous reports, SNPs at 3p12.1 were associated with PSS at genome-wide significance (p < 5.0 x 10(-8)). Furthermore, two novel loci at 9q34.2 and 4q35.2 reached suggestive significance (p < 5.0 x 10(-6)). Our data also provided evidence supporting the two additional SNPs on 2q22.3 and 9q33.2 reportedly associated with PSS. Our study reproduced previous findings in Caucasian populations and further suggested novel PSS loci in the Japanese population.
AD - Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawahigashi, Kodaira, Tokyo, 187-8502, Japan.
Department of Psychiatry, Shinshu University School of Medicine, Matsumoto, Nagano, 390-8621, Japan.
Genequest Inc., 5-22-37, Higashi-Gotanda, Shinagawa-ku, Tokyo, 141-0022, Japan.
Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawahigashi, Kodaira, Tokyo, 187-8502, Japan. [email protected].
AN - 29559738
AU - Sasayama, D.
AU - Asano, S.
AU - Nogawa, S.
AU - Takahashi, S.
AU - Saito, K.
AU - Kunugi, H.
DA - Jun
DO - 10.1038/s10038-018-0441-z
IS - 6
N1 - Sasayama, Daimei
Asano, Shinya
Nogawa, Shun
Takahashi, Shoko
Saito, Kenji
Kunugi, Hiroshi
eng
England
2018/03/22 06:00
J Hum Genet. 2018 Jun;63(6):765-768. doi: 10.1038/s10038-018-0441-z. Epub 2018 Mar 20.
PY - 2018
SN - 1435-232X (Electronic)
1434-5161 (Linking)
SP - 765-768
ST - A genome-wide association study on photic sneeze syndrome in a Japanese population
T2 - J Hum Genet
TI - A genome-wide association study on photic sneeze syndrome in a Japanese population
UR - https://www.ncbi.nlm.nih.gov/pubmed/29559738
VL - 63
ID - 123
ER -
TY - JOUR
AU - Sevillano, C.
AU - Parafita-Fernández, A.
AU - Rodriguez-Lopez, V.
AU - Sampil, M.
AU - Moraña, N.
AU - Viso, E.
AU - Cores, F. J.
DO - 10.1016/j.oftale.2016.04.007
IS - 7
PY - 2016
SN - 21735794
SP - 305-309
ST - A curious fact: Photic sneeze reflex. Autosomical dominant compelling helio-ophthalmic outburst syndrome
T2 - Archivos de la Sociedad Española de Oftalmología (English Edition)
TI - A curious fact: Photic sneeze reflex. Autosomical dominant compelling helio-ophthalmic outburst syndrome
UR - http://ac.els-cdn.com/S2173579416300214/1-s2.0-S2173579416300214-main.pdf?_tid=a74f10a6-405c-11e6-b7b8-00000aab0f6c&acdnat=1467467917_b8fd162695affc6fd905c19e05030494
VL - 91
ID - 2
ER -
TY - JOUR
AB - The sneezing reflex is a common phenomenon in human beings and animals. Until now largely uninvestigated sneezing phenomenon is the photic sneeze reflex, also known as the ACHOO (Autosomal Cholinergic Helio-Ophtalmologic Outburst). This light induced sneezing reflex is triggered by a bright light like the sun but also by artificial light. In former publications the prevalence of this phenomenon in the population is specified up to 35 % and can result in a potential endangerment in numerous everyday situations as driving a car or controlling an airplane. In our present study we interviewed 1042 patients in the Department of Otorhinolaryngology of the Saarland University Hospital using standardized questionnaires to analyse epidemiological data as age, gender and known diseases. Additionally, the questionnaire focused on the occurrence of sneezing events, extend of sneezing, potential triggers, and methods of evasion. In our data analysis, we were able to show a high prevalence of the ACHOO in 57 % of our cohort, suffering from regular light induced sneezing events. Excluding subjects reporting only occasional sneezing events our results were comparable to findings in literature. As expected a familial disposition was observed, additionally tobacco smoking correlated with light induced sneezing events. Analyzing a large cohort, we were able to demonstrate that the prevalence of the ACHOO in the german population may be higher than expected. Taken into account the potential hazard caused by this phenomenon, further investigations should identify the pathophysiologic pathway.
AD - Department of Otorhinolaryngology, Saarland University Medical Center, Kirrberger Strasse, 66421, Homburg/Saar, Germany. [email protected].
Department of Otorhinolaryngology, Saarland University Medical Center, Kirrberger Strasse, 66421, Homburg/Saar, Germany.
AN - 27568353
AU - Kulas, P.
AU - Hecker, D.
AU - Schick, B.
AU - Bozzato, A.
DA - Aug 27
DO - 10.1007/s00405-016-4256-2
KW - Achoo
Sneezing
Sun
N1 - Kulas, Philipp
Hecker, Dietmar
Schick, Bernhard
Bozzato, Alessandro
ENG
Germany
2016/08/29 06:00
Eur Arch Otorhinolaryngol. 2016 Aug 27.
PY - 2016
SN - 1434-4726 (Electronic)
0937-4477 (Linking)
ST - Investigations on the prevalence of the photo-induced sneezing reflex in the German population, a representative cross-sectional study
T2 - Eur Arch Otorhinolaryngol
TI - Investigations on the prevalence of the photo-induced sneezing reflex in the German population, a representative cross-sectional study
UR - http://www.ncbi.nlm.nih.gov/pubmed/27568353
ID - 1
ER -
TY - JOUR
AB - Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhythmia, symptomatic and non-symptomatic angina pectoris, Prinzmetal vasospastic variant angina, acute (non-fatal and fatal) incidents of myocardial infarction, sudden cardiac arrest, in-bed sudden death syndrome of type-1 diabetes, acute cardiogenic pulmonary edema, and heart failure; vascular and circulatory system ones of hypertension, acute orthostatic postprandial, micturition, and defecation hypotension/syncope, intermittent claudication, venous insufficiency, standing occupation leg edema, arterial and venous branch occlusion of the eye, menopausal hot flash, sickle cell syndrome, abdominal, aortic, and thoracic dissections, pulmonary thromboembolism, and deep venous thrombosis, and cerebrovascular transient ischemic attack and hemorrhagic and ischemic stroke. Knowledge of these temporal patterns not only helps guide patient care but research of their underlying endogenous mechanisms, i.e., circadian and others, and external triggers plus informs the development and application of effective chronopreventive and chronotherapeutic strategies.
AD - Department of Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, 1 University Station C0800, Austin, TX 78712-0238, USA. Electronic address: [email protected].
Hospital S. Anna and Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Bioengineering & Chronobiology Laboratories, University of Vigo, Campus Universitario, Vigo, Spain.
Department of Laboratory Medicine & Pathology, University of Minnesota, HealthPartners Institute for Education and Research and the Department of Pathology, Regions Hospital, St. Paul, MN, USA.
AN - 25129838
AU - Smolensky, M. H.
AU - Portaluppi, F.
AU - Manfredini, R.
AU - Hermida, R. C.
AU - Tiseo, R.
AU - Sackett-Lundeen, L. L.
AU - Haus, E. L.
DA - Jun
DO - 10.1016/j.smrv.2014.07.001
ET - 2014/08/19
KW - Circadian Rhythm/*physiology
Heart Diseases/*physiopathology
Humans
Respiratory Tract Diseases/*physiopathology
Syndrome
Vascular Diseases/*physiopathology
Circadian rhythm
Diurnal
Heart
Human disease
Morbidity
Mortality
Respiratory
Symptom intensity
Time-of-day
Vasculature
N1 - Smolensky, Michael H
Portaluppi, Francesco
Manfredini, Roberto
Hermida, Ramon C
Tiseo, Ruana
Sackett-Lundeen, Linda L
Haus, Erhard L
eng
Review
England
Sleep Med Rev. 2015 Jun;21:3-11. doi: 10.1016/j.smrv.2014.07.001. Epub 2014 Jul 18.
PY - 2015
SN - 1532-2955 (Electronic)
1087-0792 (Linking)
SP - 3-11
ST - Diurnal and twenty-four hour patterning of human diseases: cardiac, vascular, and respiratory diseases, conditions, and syndromes
T2 - Sleep Med Rev
TI - Diurnal and twenty-four hour patterning of human diseases: cardiac, vascular, and respiratory diseases, conditions, and syndromes
UR - https://www.ncbi.nlm.nih.gov/pubmed/25129838
VL - 21
ID - 146
ER -
TY - JOUR
AU - Parke, Simon
DO - 10.3233/jpn-2010-0416
IS - 04
PY - 2015
SE - 397
SN - 1304-2580
1875-9041
SP - 397-398
ST - Nothing to be sneezed at
T2 - Journal of Pediatric Neurology
TI - Nothing to be sneezed at
VL - 08
ID - 154
ER -
TY - JOUR
AB - INTRODUCTION: In patients reporting acute headache after sneezing or coughing, rupture of an intracranial aneurysm is the first diagnosis to be considered. Sneezing, however, might also be a trigger for migraine attacks, as exemplified in our case. CASE REPORT: We describe a patient who suffered 3 headache attacks after sneezing, each fulfilling criteria of migraine without aura. Sneezing as a specific trigger for migraine has not been described before. DISCUSSION: The differential diagnosis of acute headache after sneezing (eg, subarachnoid hemorrhage and reversible cerebral vasoconstriction), and the differences between migraine after sneezing and "benign cough headache" are discussed. We conclude that a pathophysiological association between migraine and sneezing might exist and hypothesize on underlying mechanisms.
AN - 23425039
AU - van Oosterhout, Willebordus P J
AU - Haan, Joost
DO - 10.1111/head.12060
KW - abbreviations
cns central nervous system
cough headache
ihs international headache society
migraine
mra magnetic resonance angiography
mri magnetic resonance imaging
pch primary cough headache
peh primary exertional headache
primary thunderclap headache
pth
sneezing
thunderclap headache
trigger factor
PY - 2013
SP - 1-5
ST - Migraine After Sneezing: Pathophysiological Considerations, Focused on the Difference With Coughing.
T2 - Headache
TI - Migraine After Sneezing: Pathophysiological Considerations, Focused on the Difference With Coughing.
ID - 14
ER -
TY - JOUR
AU - Songu, Murat
AU - Onerci, T. Metin
DO - 10.1007/978-3-642-37250-6_11
PY - 2013
SP - 139-152
ST - Physiology and Pathophysiology of Sneezing and Itching: Mechanisms of the Symptoms
TI - Physiology and Pathophysiology of Sneezing and Itching: Mechanisms of the Symptoms
UR - http://download.springer.com/static/pdf/196/chp%253A10.1007%252F978-3-642-37250-6_11.pdf?auth66=1418273486_bb40e10ac61d5fb0ff1cbe00671f7ee8&ext=.pdf
ID - 15
ER -
TY - JOUR
AN - 23680422
AU - Kulkarni, O. C.
AU - Cox, C. A.
AU - Hedges, T. R., 3rd
AU - Tarsy, D.
DA - Aug
DO - 10.1016/j.parkreldis.2013.04.014
IS - 8
J2 - Parkinsonism & related disorders
KW - Blepharospasm/diagnosis/*drug therapy
Botulinum Toxins, Type A/*administration & dosage
Female
Humans
Injections, Intraocular/*adverse effects/methods
Male
Middle Aged
Needles/*adverse effects
Reflex/*physiology
Sneezing/*physiology
N1 - Kulkarni, Omesh Chandra
Cox, Catherine A
Hedges, T R 3rd
Tarsy, Daniel
eng
Case Reports
Letter
Research Support, Non-U.S. Gov't
England
2013/05/18 06:00
Parkinsonism Relat Disord. 2013 Aug;19(8):770-1. doi: 10.1016/j.parkreldis.2013.04.014. Epub 2013 May 13.
PY - 2013
SN - 1873-5126 (Electronic)
1353-8020 (Linking)
SP - 770-1
ST - Sternutatory reflex induced by periocular needle insertion in patients receiving chronic botulinum toxin injections
T2 - Parkinsonism Relat Disord
TI - Sternutatory reflex induced by periocular needle insertion in patients receiving chronic botulinum toxin injections
UR - http://www.ncbi.nlm.nih.gov/pubmed/23680422
http://ac.els-cdn.com/S1353802013001594/1-s2.0-S1353802013001594-main.pdf?_tid=4a9a310a-80f1-11e4-b3ea-00000aab0f01&acdnat=1418273635_2477fc2138cd61f4905c8a3d6dfc7fa5
VL - 19
ID - 16
ER -
TY - JOUR
AB - Bright light can cause ocular discomfort and/or pain; however, the mechanism linking luminance to trigeminal nerve activity is not known. In this study we identify a novel reflex circuit necessary for bright light to excite nociceptive neurons in superficial laminae of trigeminal subnucleus caudalis (Vc/C1). Vc/C1 neurons encoded light intensity and displayed a long delay (>10s) for activation. Microinjection of lidocaine into the eye or trigeminal root ganglion (TRG) inhibited light responses completely, whereas topical application onto the ocular surface had no effect. These findings indicated that light-evoked Vc/C1 activity was mediated by an intraocular mechanism and transmission through the TRG. Disrupting local vasomotor activity by intraocular microinjection of the vasoconstrictive agents, norepinephrine or phenylephrine, blocked light-evoked neural activity, whereas ocular surface or intra-TRG microinjection of norepinephrine had no effect. Pupillary muscle activity did not contribute since light-evoked responses were not altered by atropine. Microinjection of lidocaine into the superior salivatory nucleus diminished light-evoked Vc/C1 activity and lacrimation suggesting that increased parasympathetic outflow was critical for light-evoked responses. The reflex circuit also required input through accessory visual pathways since both Vc/C1 activity and lacrimation were prevented by local blockade of the olivary pretectal nucleus. These findings support the hypothesis that bright light activates trigeminal nerve activity through an intraocular mechanism driven by a luminance-responsive circuit and increased parasympathetic outflow to the eye.
AN - 20206444
AU - Okamoto, Keiichiro
AU - Tashiro, Akimasa
AU - Chang, Zheng
AU - Bereiter, David a
DO - 10.1016/j.pain.2010.02.004
KW - Afferent Pathways
Afferent Pathways: physiopathology
Afferent Pathways: radiation effects
Anesthetics
Animals
Headache
Headache: etiology
Headache: physiopathology
Light
Light: adverse effects
Local
Local: pharmacology
Male
Nociceptors
Nociceptors: radiation effects
Ophthalmic Artery
Ophthalmic Artery: innervation
Ophthalmic Artery: physiopathology
Ophthalmic Nerve
Ophthalmic Nerve: physiopathology
Ophthalmic Nerve: radiation effects
Pain
Pain: etiology
Pain: physiopathology
Parasympathetic Nervous System
Parasympathetic Nervous System: drug effects
Parasympathetic Nervous System: physiology
Photophobia
Photophobia: etiology
Photophobia: physiopathology
Rats
Regional Blood Flow
Regional Blood Flow: drug effects
Regional Blood Flow: physiology
Rhombencephalon
Rhombencephalon: drug effects
Rhombencephalon: physiology
Sprague-Dawley
Trigeminal Caudal Nucleus
Trigeminal Caudal Nucleus: physiopathology
Trigeminal Caudal Nucleus: radiation effects
Trigeminal Ganglion
Trigeminal Ganglion: physiopathology
Trigeminal Ganglion: radiation effects
Trigeminal Nerve
Trigeminal Nerve: physiopathology
Trigeminal Nerve: radiation effects
Vasoconstrictor Agents
Vasoconstrictor Agents: pharmacology
Vasodilation
Vasodilation: drug effects
Vasodilation: physiology
Visual Pathways
Visual Pathways: drug effects
Visual Pathways: physiopathology
PY - 2010
SP - 235-42
ST - Bright light activates a trigeminal nociceptive pathway.
T2 - Pain