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samtools depth does not output positions with zero coverage #5

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mfoll opened this issue May 4, 2016 · 2 comments
Open

samtools depth does not output positions with zero coverage #5

mfoll opened this issue May 4, 2016 · 2 comments

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@mfoll
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mfoll commented May 4, 2016

This means that the estimated coverage can be biased, as the zeros are not counted when calculating the mean/median coverage? samtools depth now offers an option (-a) to resolve this so it should be straightforward:
samtools/samtools#374

@slzhao
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slzhao commented May 4, 2016

Thanks, Matthieu! Added it.

Best,
Shilin

2016-05-04 7:03 GMT-05:00 Matthieu Foll [email protected]:

This means that the estimated coverage can be biased, as the zeros are not
counted when calculating the mean/median coverage? samtools depth now
offers an option (-a) to resolve this so it should be straightforward:
samtools/samtools#374 samtools/samtools#374


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#5

@mfoll
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mfoll commented May 5, 2016

Great thanks, will try it and let you know.

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