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new module: Portcullis #7310

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4 tasks done
jblancoheredia opened this issue Jan 15, 2025 · 1 comment
Open
4 tasks done

new module: Portcullis #7310

jblancoheredia opened this issue Jan 15, 2025 · 1 comment
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new module Adding a new module

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@jblancoheredia
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Is there an existing module for this?

  • I have searched for the existing module

Is there an open PR for this?

  • I have searched for existing PRs

Is there an open issue for this?

  • I have searched for existing issues

Further Information
Portcullis (PORTable CULLing of Invalid Splice junctions) is a tool for filtering invalid splice junctions from pre-aligned RNA-seq data.
The tool:

  • Takes BAM files as input from any RNAseq mapper (e.g., Tophat2, Gsnap, STAR2, HISAT2)
  • Analyzes and quantifies all splice junctions in the input file
  • Filters (culls) splice junctions that are likely invalid, particularly in deep datasets with high coverage
  • Outputs junctions in multiple formats for downstream analysis (differential splicing analysis, gene modeling)
  • Works independently of the mapper, making it portable across different RNA-seq analysis pipelines

Are you going to work on this?

  • I plan to work on this but don't have permissions to add myself to Assignees or add "new module" in Labels.
@jblancoheredia
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I would like to work on implementing this module. Could a maintainer please add the appropriate labels and assign this issue to me?

@jblancoheredia jblancoheredia self-assigned this Jan 23, 2025
@jblancoheredia jblancoheredia added the new module Adding a new module label Jan 23, 2025
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