diff --git a/tox.ini b/tox.ini
index e5efda8..da5d82e 100644
--- a/tox.ini
+++ b/tox.ini
@@ -39,7 +39,15 @@ deps =
     napari[pyqt5,testing]
     lxml_html_clean # should only be needed till napari 0.5.0
 
-[testenv:py{38,39,310}-{linux,macos,windows}-pyside]
+# napari is experiencing CI failures with PySide backends
+# on Windows platforms for all versions of python, and
+# on all platforms with python 3.11
+# See issues:
+# Python 3.11 PySide problems https://github.com/napari/napari/issues/6381
+# and https://github.com/napari/napari/issues/5884#issuecomment-1584160532
+# Windows PySide problems https://github.com/napari/napari/pull/6721/files
+# and https://github.com/napari/napari/pull/6711/
+[testenv:py{38,39,310}-{linux,macos}-pyside]
 deps =
     napari[pyside2,testing]
     lxml_html_clean # should only be needed till napari 0.5.0