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Non-recombinant: XAN #353

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szhan opened this issue Feb 25, 2025 · 1 comment
Open

Non-recombinant: XAN #353

szhan opened this issue Feb 25, 2025 · 1 comment

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@szhan
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szhan commented Feb 25, 2025

cov-lineages/pango-designation#771

ktmeaton/ncov-recombinant#109

Below is info collated from the pango-designation issues by the RecombinHunt authors.

method left_parent right_parent left_breakpoint right_breakpoint
pango-designation BA.2* BA.5.1 17822 21766

Discussion started #285.

Quoting Yan: "Slightly less sure, with multiple recurrent/reversion mutations, but XAV and XAN may not be recombinants."

Coping image from Yan.
Image

@szhan szhan changed the title Non-recombinant: XAV Non-recombinant: XAN Feb 25, 2025
@szhan
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szhan commented Feb 25, 2025

It is detected a recombinant by both RecombinHunt-GISAID and RecombinHunt-Nextstrain.

method left_parent right_parent left_breakpoint right_breakpoint
RecombinHunt-GISAID BJ.1 BA.5.1.23 9866 9867
RecombinHunt-Nextstrain BA.2 BA.5.1.23 9866 9867

N.B. I checked again with SupplementaryNotes2_RH_gisaid_sarscov2_detail.html. The breakpoint intervals are way off compared to the ground truth.

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