diff --git a/scanpy_scripts/lib/_pca.py b/scanpy_scripts/lib/_pca.py
index 28efc80f..eb58b459 100644
--- a/scanpy_scripts/lib/_pca.py
+++ b/scanpy_scripts/lib/_pca.py
@@ -4,6 +4,7 @@
 
 import logging
 import scanpy as sc
+import math
 from ..obj_utils import write_embedding
 
 
@@ -12,6 +13,10 @@ def pca(adata, key_added=None, export_embedding=None, **kwargs):
     Wrapper function for sc.pp.pca, for supporting named slot
     """
 
+    # Check the number of components (n_comps) less than floor(number of genes)/2
+    if 'n_comps' in kwargs and kwargs['n_comps'] is not None:
+        kwargs['n_comps'] = min(math.floor(adata.n_vars/2) -1, kwargs['n_comps'])
+
     # omit "svd_solver" to let scanpy choose automatically
     if "svd_solver" in kwargs and kwargs["svd_solver"] == "auto":
         del kwargs["svd_solver"]