diff --git a/requirements.txt b/requirements.txt
index d13c91e3b..f635be815 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1115,9 +1115,9 @@ zipp==3.19.1 \
     # via importlib-metadata
 
 # The following packages are considered to be unsafe in a requirements file:
-setuptools==70.0.0 \
-    --hash=sha256:54faa7f2e8d2d11bcd2c07bed282eef1046b5c080d1c32add737d7b5817b1ad4 \
-    --hash=sha256:f211a66637b8fa059bb28183da127d4e86396c991a942b028c6650d4319c3fd0
+setuptools==75.1.0 \
+    --hash=sha256:35ab7fd3bcd95e6b7fd704e4a1539513edad446c097797f2985e0e4b960772f2 \
+    --hash=sha256:d59a21b17a275fb872a9c3dae73963160ae079f1049ed956880cd7c09b120538
     # via
     #   -r requirements.in
     #   opentelemetry-instrumentation