Beta-pairing Binder Design Script?

[amelie-iska]

Hi all,
I'm sure everyone knows how much I love RFdiffusion by now, but thanks all the same. Any chance you all could push the script(s) used for the beta-pairing binder design strategy you recently published? I've been having a lot of trouble replicating it. I thought one needed to use helper_scripts/make_secstruc_adj.py to get the appropriate biasing vector and matrix. However, it's not entirely clear to me I'm even doing this step properly, and I have not been able to run the model with this biasing info to get a binder with a beta strand paired with a beta strand in the target. If you are able to share more, that would be very helpful!

Tschüss!
Amelie