Getting Started

Introduction

Welcome to the CALYPSO study feasibility application. For this introduction, it is assumed that the application, database and OHDSI WebAPI have already been installed. If not, please contact your administrator and refer to the [Setup Guide] (Setup Guide) for installation instructions.

What is CALYPSO?

CALYPSO (Criteria Assessment Logic for Your Population Study in Observational data) is a browser-based application that utilizes real world data (RWD) to simulate the availability of eligible patients for a study. The tool allows users to define the index rule (primary condition under study) and inclusion rules (inclusion/exclusion criteria) and run feasibility simulations against the RWD (health insurance claims and electronic medical records). The tool allows users to visualize which inclusion/exclusion criteria have the largest impact on the availability of patients within the RWD. The index population are those patients as defined by the index rule and the matching population are those patients that meet all of the inclusion rules or those patients that you would expect to be eligible to enroll into the trial under evaluation. Using this tool can help to identify inclusion/exclusion criteria that could be limiting to study feasiblity. The tool can be used to run multiple scenarios against any study criteria to help expedite decision making.

Browser Requirements

Due to some of the advanced features for visualizations, the application requires either Google Chrome or Internet Explorer 10+.

Using the Application

To launch CALYPSO, navigate to the URL where the CALYPSO site was installed (ex: http://yourdomain.com/CALYPSO). From this URL, you are presented with the list of existing feasibility studies and a button to 'Create New Study'. For this short overview, we will create a simple study and view the simulation results.

Create a New Study