diff --git a/.github/workflows/setup.yml b/.github/workflows/setup.yml
index e00217f2..b79bdd52 100644
--- a/.github/workflows/setup.yml
+++ b/.github/workflows/setup.yml
@@ -27,6 +27,9 @@ jobs:
             cmd: jupyter nbconvert --to HTML tutorials/jupyter/supplementary_material.ipynb
           - env: quarto
             cmd: conda install -c conda-forge quarto && conda install -c conda-forge deno && export QUARTO_DENO=$(which deno) && quarto render tutorials/quarto/quarto-tutorial-example.qmd --to html
+        exclude:
+          - os: macos-latest
+            env: [snakemake, nextflow]
     steps:
       - name: Checkout
         uses: actions/checkout@v4