README.md

On the Genes, Genealogies, and Geographies of Quebec

Free-access link to Science paper : link

Supplementary code related to a manuscript entitled "On the Genes, Genealogies, and Geographies of Quebec".

The authors of this manuscript are :

Luke Anderson-Trocmé, Dominic Nelson, Shadi Zabad, Alex Diaz-Papkovich, Ivan Kryukov, Nikolas Baya, Ben Jeffery, Mathilde Touvier, Christian Dina, Hélène Vézina, Jerome Kelleher, Simon Gravel

French abstract here

msprime genome simulations

Whole genome simulations of 1.4 million individuals are freely available on Zenodo.

Pipelines related to genome simulation are available here.

tskit and msprime provide extensive documentation about the fixed pedigree simulations used in this paper.

Folders with Supplementary Code

• cross_coalescence: compute genealogically based coalescence rates

• data_viz: generate main figures of manuscript

• watershed_enrichment: compute watershed enrichment statisitics

Links to Geographical Data

The geographical data used for this publication can be found on Open Canada geo base accessed through https://open.canada.ca/.

The National Hydro Network GeoBase Series can be found here.

The Canadian Digital Elevation Model GeoTIF files can be found here

Main Figures

For more information, please refer to the PDF