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Copy pathgeroconversion.cfg
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geroconversion.cfg
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$u_Insulin=1;
$d_Insulin=1;
$u_GF=1;
$d_GF=1;
$u_Senescence=1;
$d_Senescence=1;
$u_G1_S=1;
$d_G1_S=1;
$u_MAPK=1;
$d_MAPK=1;
$u_p16=1;
$d_p16=1;
$u_MDM2=1;
$d_MDM2=1;
$u_p53=1;
$d_p53=1;
$u_p21=1;
$d_p21=1;
$u_AKT=1;
$d_AKT=1;
$u_mTORC1_S6K1=1;
$d_mTORC1_S6K1=1;
$u_ATP=1;
$d_ATP=1;
$u_IRS_PIK3CA=1;
$d_IRS_PIK3CA=1;
$u_AMPK=1;
$d_AMPK=1;
$u_PTEN=1;
$d_PTEN=1;
$u_TSC=1;
$d_TSC=1;
$u_MYC=1;
$d_MYC=1;
$u_CDK2=1;
$d_CDK2=1;
$u_RB1=1;
$d_RB1=1;
$u_E2F1=1;
$d_E2F1=1;
$u_PRC=1;
$d_PRC=1;
$u_Metabolism=1;
$d_Metabolism=1;
$u_PP2A=1;
$d_PP2A=1;
$u_FOXO=1;
$d_FOXO=1;
$u_PP1C=1;
$d_PP1C=1;
Insulin.is_internal=1;
GF.is_internal=1;
Senescence.is_internal=0;
G1_S.is_internal=0;
MAPK.is_internal=1;
p16.is_internal=1;
MDM2.is_internal=1;
p53.is_internal=1;
p21.is_internal=1;
AKT.is_internal=1;
mTORC1_S6K1.is_internal=1;
ATP.is_internal=1;
IRS_PIK3CA.is_internal=1;
AMPK.is_internal=1;
PTEN.is_internal=1;
TSC.is_internal=1;
MYC.is_internal=1;
CDK2.is_internal=1;
RB1.is_internal=1;
E2F1.is_internal=1;
PRC.is_internal=1;
Metabolism.is_internal=1;
PP2A.is_internal=1;
FOXO.is_internal=1;
PP1C.is_internal=1;
discrete_time = 0;
use_physrandgen = FALSE;
seed_pseudorandom = 100;
sample_count = 50000;
max_time = 400;
time_tick = 0.1;
thread_count = 4;
statdist_traj_count = 100;
statdist_cluster_threshold = 0.9;