diff --git a/.github/workflows/profiling-native.yml b/.github/workflows/profiling-native.yml
new file mode 100644
index 00000000000..98722552dbd
--- /dev/null
+++ b/.github/workflows/profiling-native.yml
@@ -0,0 +1,48 @@
+name: Profiling Native Tests with Sanitizers
+
+on:
+  push:
+    branches:
+      - main
+      - "mq-working-branch**"
+  pull_request:
+    paths:
+    - ddtrace/internal/datadog/profiling/**
+    - ddtrace/profiling/**
+  workflow_dispatch: {}
+
+jobs:
+  test:
+    runs-on: ${{ matrix.os }}
+    timeout-minutes: 5
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [ubuntu-24.04]
+        python-version: ["3.8", "3.9", "3.10", "3.11", "3.12"]
+        sanitizer: ["safety", "thread"]
+
+    steps:
+      - uses: actions/checkout@v4
+        with:
+          persist-credentials: false
+          fetch-depth: 1
+
+      - uses: actions/setup-python@v5
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Install llvm 19
+        run: |
+          # Ubuntu-24.04 GH actions image has llvm-18, but we use 19 as it's
+          # the latest one available.
+          wget https://apt.llvm.org/llvm.sh
+          chmod +x llvm.sh
+          sudo ./llvm.sh 19
+
+      - name: Run tests with sanitizers
+        run: |
+          # DEV: We currently have tests in dd_wrapper and stack_v2, setting
+          # stack_v2 here will also run tests in dd_wrapper. Revisit this when
+          # that changes.
+          ./ddtrace/internal/datadog/profiling/build_standalone.sh --${{matrix.sanitizer}} RelWithDebInfo stack_v2_test
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/test/CMakeLists.txt b/ddtrace/internal/datadog/profiling/dd_wrapper/test/CMakeLists.txt
index 6a1e7f406f6..0be6098cd2a 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/test/CMakeLists.txt
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/test/CMakeLists.txt
@@ -21,7 +21,12 @@ function(dd_wrapper_add_test name)
     target_link_libraries(${name} PRIVATE gmock gtest_main dd_wrapper nlohmann_json::nlohmann_json)
     add_ddup_config(${name})
 
-    gtest_discover_tests(${name})
+    gtest_discover_tests(${name}
+        PROPERTIES
+            # We start new threads after fork(), and we want to continue
+            # running the tests after that instead of dying.
+            ENVIRONMENT "TSAN_OPTIONS=die_after_fork=0:suppressions=${CMAKE_CURRENT_SOURCE_DIR}/TSan.supp"
+    )
 
     set_target_properties(${name} PROPERTIES INSTALL_RPATH "$ORIGIN/..")
 
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/test/TSan.supp b/ddtrace/internal/datadog/profiling/dd_wrapper/test/TSan.supp
new file mode 100644
index 00000000000..bc9e9d23668
--- /dev/null
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/test/TSan.supp
@@ -0,0 +1,4 @@
+# libdd is not compiled with sanitizers so probably that's why we get these
+# data races from ddog_ArrayQueue and Datadog::Sample operations
+race:ddog_ArrayQueue
+race:Datadog::Sample::
diff --git a/ddtrace/internal/datadog/profiling/stack_v2/CMakeLists.txt b/ddtrace/internal/datadog/profiling/stack_v2/CMakeLists.txt
index 9fc78ee8046..50c8d056c79 100644
--- a/ddtrace/internal/datadog/profiling/stack_v2/CMakeLists.txt
+++ b/ddtrace/internal/datadog/profiling/stack_v2/CMakeLists.txt
@@ -37,7 +37,7 @@ endif()
 
 # Add echion
 set(ECHION_COMMIT
-    "9d5bcc5867d7aefff73c837adcba4ef46eecebc6"
+    "ed744987f224fae3f93c842b2b5ffb083984ff8b"
     CACHE STRING "Commit hash of echion to use")
 FetchContent_Declare(
     echion